نتایج جستجو برای: avermectin h2b1b
تعداد نتایج: 247 فیلتر نتایج به سال:
A stereodivergent approach to the spiroketal fragment of the avermectins is described. The strategy utilizes a sequence of three aldol reactions directed by the tris(trimethylsilyl)silyl "super silyl" group. Central to this strategy is that each aldol reaction can be controlled to allow access to either diastereomer in high stereoselectivity, thereby affording 16 stereoisomers along the same li...
OBJECTIVE To evaluate the safety of moxidectin administration at doses of 30, 60, and 90 microg/kg of body weight (10, 20, and 30 times the manufacturer's recommended dose) in avermectin-sensitive Collies. ANIMALS 24 Collies. PROCEDURE Collies with mild to severe reactions to ivermectin challenge (120 mg/kg; 20 times the recommended dose for heartworm prevention) were used. Six replicates o...
The effect treatments with the recommended application rates of avermectin, buprofezin, white oil, lambda-cyhalothrin and cyromazine on Trialeurodes vaporariorum Westwood (Aleyrodidae: Homoptera) was evaluated. Pesticides were applied against larvae infesting brinjal (Solanum melongena L.) and tomato (Lycopersicon esculentum Mill) plants in a natural environment of the Cameron Highlands, Pahang...
Discovered in the late-1970s, the pioneering drug ivermectin, a dihydro derivative of avermectin--originating solely from a single microorganism isolated at the Kitasato Institute, Tokyo, Japan from Japanese soil--has had an immeasurably beneficial impact in improving the lives and welfare of billions of people throughout the world. Originally introduced as a veterinary drug, it kills a wide ra...
Invasive diseases of horses are an urgent problem in the horse breeding industry Republic Belarus, as well near and far abroad countries. The main role among parasitic pathology is occupied by helminths small large intestine, larvae gasterophilus. In associative course, they cause significant economic losses associated with growth development sick young animals, reduced performance, endurance i...
Our laboratory is investigating ivermectin (IVM) and other members of the avermectin family as new pharmaco-therapeutics to prevent and/or treat alcohol use disorders (AUDs). Earlier work found that IVM significantly reduced ethanol intake in mice and that this effect likely reflects IVM's ability to modulate ligand-gated ion channels. We hypothesized that structural modifications that enhance ...
Heavy-ion irradiation technology has advantages over traditional methods of mutagenesis. Heavy-ion irradiation improves the mutation rate, broadens the mutation spectrum, and shortens the breeding cycle. However, few data are currently available regarding its effect on Streptomyces avermitilis morphology and productivity. In this study, the influence of heavy-ion irradiation on S. avermitilis w...
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