The use of domino and multicomponent reactions in asymmetric synthesis is constantly increasing nowadays. This allows for the synthesis of complex molecules in a single synthetic sequence, usually with high atom economy. Herein, we report three examples of new asymmetric tandem reactions recently developed in our laboratories, giving rise to new families of enantiomerically enriched fluorinated...

Frontispiece: In article number 2100063 by Patrick Theato, Hatice Mutlu, and Edgar Molle, a set of novel poly(N-(4-vinylphenyl)sulfonamide) s featuring varying electron densities is prepared in straightforward fashion subsequently used post-polymerization modification reactions via aza-Michael addition with different electron-defi cient alkenes as Michael acceptors for the facile synthesis poly...

In this work we will report the formulation of novel 3-(pyridinylamino)-1-ferrocenylpropan-1-ones. A fruitful aza-Michael addition pyridinamine moiety to a conjugated enone, 1-ferrocenylpropenone, has been accomplished by an ultrasonic irradiation mixture these reactants. As catalyst montmorillonite K-10 used and reaction carried out as solvent-free, yielding ferrocene containing Mannich bases,...

1,1-dicyanovinyl push-pull dye PTTCN undergoes rapid and reversible aza-Michael addition with volatile primary aliphatic amines in solution DMSO, yielding highly fluorescent imine derivatives. This reaction is accompanied by a dramatic colour change as well strong increase fluorescence (1200-fold increase) allowing sensitive turn-on detection of amine solution. In the solid state, emissive vapo...

A one-pot, two step synthesis of highly substituted imidazoles has been carried out in good to excellent yields for the first time via a cascade intermolecular aza-SN2'-intramolecular aza-Michael addition involving a variety of Morita-Baylis-Hillman acetates of nitroalkenes and amidines in the presence of DABCO at room temperature. The synthetic and biological utility of the products has been d...

2.1.8. Michael Reaction 2245 2.1.9. Others 2247 2.2. Cyclization Reactions 2248 2.2.1. Carbon Diels−Alder Reactions 2248 2.2.2. Aza-Diels−Alder Reactions 2252 2.2.3. Other Hetero-Diels−Alder Reactions 2255 2.2.4. Ionic Diels−Alder Reaction 2256 2.2.5. 1,3-Dipolar Cycloadditions 2256 2.2.6. Other Cycloaddition Reactions 2258 2.2.7. Prins-type Cyclization 2259 2.3. Friedel−Crafts Acylation and Al...