Background & Objective: Although the antigen expression patterns of acute lymphoblastic leukemia (ALL) are well known, this study attempted to evaluate commonly used immune markers for immunophenotyping of acute leukemia to set the minimum of necessary diagnostic panels by flow cytometry. Methods: This study evaluated 89 patients referred from all over th...

primary hepatic lymphoma is a rare malignancy usually presenting with symptoms of fever, hepatomegaly, jaundice and weight loss. this picture mimics infectious and inflammatory disorders and thus delays the diagnosis. here, we present a 47-year old man with prolonged fever who underwent several investigations and, in the meantime, developed fulminant hepatic failure before the diagnosis could b...

cd19 is expressed on b- lineage cells and follicular dendritic cells and plays a key role in b cell malignancies and autoimmune diseases. thus, it has been considered as potential target for several monoclonal antibodies (mabs). for decades, chemotherapy has been known as one of the major antitumor therapies eradicating high proliferative tumor cells. but, anti- cd19 mabs developed for treating...

we report a case of membranoproliferative glomerulonephritis (mpgn) with igmκ light chain deposits in a patient with chronic hepatitis c infection and simultaneous onset of monoclonal igmκ gammopathy with concurrent small b-cell lymphoproliferative disease. the patient presented with hepatosplenomegaly and a uremic state that necessitated dialysis without any clinical signs of systemic disease ...

Abstract B-cell lymphoblastic lymphoma (B-LBL) is an uncommon subtype of pediatric non-Hodgkin Lymphoma (NHL) which rarely involves the skin primarily. The positron emission tomography with 2-deoxy-2-[fluorine- 18] fluoro-D: -glucose integrated with computed tomography (18F-FDG PET/CT) scan findings of a 8-year-old boy with cutaneous B-LBL were presented. PET/CT scan demonstrated mild FDG up...

Diffuse large B-cell lymphoma can selectively and predominantly infiltrate lymph node sinuses this pattern has been recognized as an unusual morphologic variant of entity. Sinusoidal lymphomas with CD30 expression are even more rare.We present a 63-year-old female, who came in chief complaint mass the axillar region for 2 months. The lymphnode ultrasound revealed multiple suspicious lymphadenop...

A Granulomatous lesion in the skin is a common finding and cutaneous lymphoma, although less common, not rare entity. However few case reports exist of granulomatous harboring lymphoma. We present 72-year-old male, with no known co morbidities presenting painless erythematous papules nodules over forehead, trunk limbs since 10 days. The biopsy from showed granulomas along giant cells diffuse mo...