نتایج جستجو برای: b7 h4

تعداد نتایج: 9051  

2014
Joanne Leung Woong-Kyung Suh

The interactions between B7 molecules and CD28-family receptors are crucial in the regulation of adaptive cellular immunity. In cancer, the aberrant expression of co-inhibitory B7 molecules has been attributed to reduced anti-tumor immunity and cancer immune evasion, prompting the development of cancer therapeutics that can restore T cell function. Murine tumor models have provided significant ...

2010
Garnet L. Anderson Martin McIntosh Lieling Wu Matt Barnett Gary Goodman Jason D. Thorpe Lindsay Bergan Mark D. Thornquist Nathalie Scholler Nam Kim Kathy O'Briant Charles Drescher Nicole Urban

BACKGROUND CA125, human epididymis protein 4 (HE4), mesothelin, B7-H4, decoy receptor 3 (DcR3), and spondin-2 have been identified as potential ovarian cancer biomarkers. Except for CA125, their behavior in the prediagnostic period has not been evaluated. METHODS Immunoassays were used to determine concentrations of CA125, HE4, mesothelin, B7-H4, DcR3, and spondin-2 proteins in prediagnostic ...

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