Glycans are essential components in maintaining many important biological processes within the body, and can be found in forms ranging from simple monomers to complex polymeric assemblies. On the cell surface, oligosaccharides are presented and recognized by an array of carbohydrate-binding proteins (lectins), such as sialic acid-binding Ig-like lectins (Siglecs), selectins, and galectins. The ...

We describe a new approach to employing specifications for software reliability. Rather than only using specifications to validate implementations, we additionally employ specifications as a reliable alternative to those implementations. Our approach, which we call Plan B, performs dynamic contract checking of methods. However, instead of halting the program upon a contract violation, we employ...

Previously published Photo Quizzes are now featured in a mobile app. Get more information at http:/www. aafp.org/afp/apps. A 44-year-old man on active duty in the Marines presented with a dry, red patch of skin on his back that had been present for two days. The rash was pruritic and painful to touch. There was no discharge from the lesion. The patient did not have fever or new environmental co...