We have isolated and characterized Dictyostelium discoideum mutants with conditional defects in phagocytosis. Under suspension conditions, the mutants exhibited dramatic reductions in the uptake of bacteria and polystyrene latex beads. The initial binding of these ligands was unaffected, however, indicating that the defect was not in a plasma membrane receptor: Because of the phagocytosis defec...

1. The irradiation of bacteria in liquid suspension has been made possible through: (a) the use of a specially balanced physiological salt solution which is practically non-absorbing for the wave lengths used, and which is of such composition that subsequent dilution of the bacterial suspension gives the proper number of organisms; (b) special design of the exposure cell and a very thorough met...

OBJECTIVE(S) Urinary tract infection (UTI) caused by bacteria is one of the most frequent infections in human population. Inappropriate use of antibiotics, often leads to appearance of drug resistance in bacteria. However, use of probiotic bacteria has been suggested as a partial replacement. This study was aimed to assess the antagonistic effects of Lactobacillus standard strains against bacte...

The potential of focussed beam reflectance measurement (FBRM) as a tool to monitor changes in biomass concentration was investigated in a number of biological systems. The measurement technique was applied to two morphologically dissimilar plant cell suspension cultures, Morinda citrifolia and Centaurea calcitrapa, to a filamentous bacteria, Streptomyces natalensis, to high density cultures of ...

Objectives Periodontal diseases are one of the common oral diseases and microbial oral flora is one major factor responsible for it. Elimination of periodontal pathogens is particularly important in managing the periodontal state. This study aimed to assess the antibacterial effects of Nanosil, chlorhexidine (CHX) and probiotic mouthwashes on periodontal pathogens. Methods In this in-vitro stu...

Bacteria are the most abundant organisms on Earth and they significantly influence carbon cycling and sequestration, decomposition of biomass, and transformation of contaminants in the environment. This motivates our study of the basic principles of bacterial behavior and its control. The principal mechanism behind the unique macroscopic properties of bacterial suspensions (e.g., 7-fold reducti...

Bacteria are the most abundant organisms on Earth and they significantly influence carbon cycling and sequestration, decomposition of biomass, and transformation of contaminants in the environment. This motivates our study of the basic principles of bacterial behavior and its control. The principal mechanism behind the unique macroscopic properties of bacterial suspensions (e.g., 7-fold reducti...

Conventional ophthalmic dosage forms have lower bioavailability due to many factors like precorneal loss factor, tear dynamics, low residence time etc. Another reason for lower bioavailability is lower permeation of conventional dosage form. This research is based on formulation of liposomal suspension to increase the lipophilic cornea. This liposomal suspension was converted in to hydogel usin...