Objective: To compare the mycobacteriological yield from self-expectorated sputum (SP), gastric lavage (GL) and bronchoalveolar lavage (BAL), in children with pulmonary tuberculosis (TB). Methods: Twelve children with cultureor PCR-positive pulmonary TB were retrospectively enrolled in this study. These patients had undergone SP collection, GL and/or BAL through flexible bronchoscopy. Positive ...

STUDY OBJECTIVES To examine the peripheral effects of BAL on the neutrophil counts and cytokine levels in the circulation. DESIGN AND METHODS WBC counts and plasma cytokines were measured before and 4 h after fiberoptic bronchoscopy (FOB) without further interventions (n = 6), or combined with BAL in normal volunteer subjects (n = 6), and in patients with bacterial pneumonia (n = 4). The bron...

Bacterial colonization of the lower airways in patients with chronic bronchitis (CB) has been described mainly in patients with co-existing chronic obstructive pulmonary disease (COPD). Although smoking has been identified as a risk factor for bacterial colonization it is not known whether asymptomatic smokers (AS) can be colonized. The aim of this study was to study lower airway bacterial colo...

The aim of the present study was to evaluate the clinical role of bronchoscopic and nonbronchoscopic bronchoalveolar lavage (BAL) in the diagnosis of infectious and interstitial lung disease in children. BAL was performed using three 1 mL.kg-1 aliquots of normal saline, with the flexible bronchoscope (Olympus 3.6 or 4.8 mm) wedged in a segmental or subsegmental bronchus of the lobe that showed ...

Background: Serum lactate dehydrogenase (LDH) concentration is an indicator for tissue injury. It may be secreted locally in many conditions. For the first time, this study was performed to investigate the value of LDH level in bronchoalveolar lavage fluid (BALF) in differentiation of benign from malignant single pulmonary nodules (SPNs) and to assess its relationship with serum LDH levels. Met...

BACKGROUND The usefulness of bronchoalveolar lavage (BAL) fluid cellular analysis in pneumonia has not been adequately evaluated. This study investigated the ability of cellular analysis of BAL fluid to differentially diagnose bacterial pneumonia from viral pneumonia in adult patients who are admitted to intensive care unit. METHODS BAL fluid cellular analysis was evaluated in 47 adult patien...

BACKGROUND The incidence of pneumococcal pneumonia is greatly increased among human immunodeficiency virus (HIV)-infected subjects, compared with among non-HIV-infected subjects. Lung fluid levels of immunoglobulin G (IgG) specific for pneumococcal capsular polysaccharide are not reduced in HIV-infected subjects; therefore, we examined immunoglobulin subtypes and compared lung fluid IgG opsonic...

During the period 1941-5, studies were conducted in this laboratory on the antidotal action of 2:3dimercaptopropanol (BAL, British Anti-Lewisite) and other thiols in arsenic poisoning; for review see Young (1946). The investigations were undertaken after receiving early reports of the work of Peters and his co-workers on the value of 2:3-dimercaptopropanol as an antidote to arsenic. In 1945 Pet...

We have carried out the first systematic survey of the sub-millimeter properties of broad absorption line (BAL) quasars. 30 BAL quasars drawn from a homogeneously selected sample from the Sloan Digital Sky Survey at redshifts 2 < z < 2.6 were observed with the SCUBA array at the JCMT to a typical rms sensitivity of 2.5mJy. Eight quasars were detected at > 2σ significance, four of which are at >...

BACKGROUND Patients treated for hematological malignancies have an increased risk of serious infections. Diagnosis and prompt initiation of therapy are essential. Bronchoalveolar lavage (BAL) is a well-established investigation for identifying the cause of pulmonary infiltrates in immunocompromised patients. The aim of the study was to determine the diagnostic yield of BAL in patients treated f...