To clarify behavior and sliding resistance of a spread foundation under combined load, static vertical loading test, lateral tests were conducted on sand. The the load was caused by soil failure beneath foundation. After peak resistance, settlement horizontal displacement increased although did not increase. When is less than about 1/2 ultimate bearing capacity, could be retained greater settle...

A novel bridged nucleic acid bearing cyclic urea structure was successfully synthesized and introduced into oligonucleotide, displaying attractive characteristics of highly RNA selective hybridization ability and excellent resistance towards nuclease degradation.

Acquired and intrinsic resistance still remains a limitation to the clinical use of 5-fluorouracil (5-FU). The contribution of epigenetic changes to the development of drug resistance remains to be elucidated. Several genes that are hypermethylated and silenced have been identified in colorectal cancer. Based on the findings described in the accompanying article, we hypothesized that acquired r...

This study examined the effectiveness of resistance exercise as a countermeasure to non-weight-bearing-induced alterations in the absolute peak force, normalized peak force (force/fiber cross-sectional area), peak stiffness, and maximal shortening velocity (Vo) of single permeabilized type I soleus muscle fibers. Adult rats were subjected to the following treatments: normal weight bearing (WB),...

seismic base isolation are devices that used to limit the human and material damage caused by an earthquake. this devices diffuse the energy induced at the time of the earthquake before being transferred to the structure.the base isolated structures when subjected to the near-fault eathquakes which contain long-period velocity pulses that may coincide with the period of base isolated structures...