PURPOSE to explore the clinical value of 3.0T magnetic resonance (MR) imaging compared with computer-aided MR diagnosis (MR-CAD) in differential diagnosis of benign and malignant breast tumors. MATERIALS AND METHODS MRI method and MR-CAD method was used in the diagnosis of a total of 93 breast lesions of 78 patients, based on the morphological and time-intensity-curve (TIC) analysis. The accu...

metallothionein (mt) manifests varying expression levels in carcinomas, and they may be considered as valuable cell cancerization biomarkers for diagnosis of patients with cancers. a meta-analysis was conducted to evaluate comprehensively the mt expression difference in various benign tumors and malignant tumors, which compared the high with low mt expression levels in patients of the available...

Loss of expression of cadherin-11 protein is correlated with a loss of epithelial phenotype and a gain in tumor cell proliferation and invasion. It has been hypothesized that cadherin-11 may be a molecular marker for a more aggressive subtype of breast cancer. The present study examined the expression of the mesenchymal gene/protein cadherin-11 in malignant, benign and healthy breast cancer sam...

INTRODUCTION Benign Osseous metaplasia of the breast is rare, with only a few cases reported in the literature. Here we present a case of benign osseous metaplasia of the breast presenting as a breast lump. CASE PRESENTATION 38-year-old previously well woman presented with a one-year history of bilateral breast pain and a left-sided breast lump. Ultrasound and mammography suggested calcified ...

Authors performed an immunohistochemical analysis using monoclonal antibody to p53 protein on 15 cases of benign and malignant phyllodes tumor of the breast along with a review of other conventional clinicopathological parameters to investigate the meaning of p53 expression. The cases were composed of 8 benign and 7 malignant lesions. The pattern of p53 expression showed a statistically signifi...

background and aims. although salivary gland tumors are not very common, early diagnosis and treatment is crucial because of their proximity to vital organs, and therefore, determining the efficacy of new imaging procedures becomes important. this study aimed to evaluate the efficacy of magnetic resonance imaging (mri) and color doppler ultrasonography parameters in the diagnosis and differenti...

the evaluate the diagnostic value of image guided fine needle aspiration (fna) in breast lesions, the cytologic results of 401 patients were studied. all patients had either unpalpable masses or lesions who were hardly possible to localize by palpation and fna was performed by single radiologist under ultrasound guide in all cases. the cytologic results were divided into four categories (inconc...

conclusion serum cyfra21-1 is useful as a measure in differentiating malignant from benign pleural effusion. results there was statistically significant difference between mean of serum cyfra21-1 levels of benign (3.9±7.6) and malignant(19.5± 30) pleural effusion (p=0.01). in addition the sensitivity, specificity, positive predictive value and negative predictive value of serum cyfra21-1 at the...

 ABSTRACT Background: Evaluation of breast masses in women under 40 years old starts with a Triple Test Score (TTS) which is composed of clinical breast examination, mammography and fine needle aspiration. Increased breast density in this age group decreases the sensitivity of mammography. So deciding whether to biopsy such nondiagnostic lesions or not is subject to challenge. Breast masses up ...

OBJECTIVE Phyllodes Tumor is a rare fibroepithelial breast tumor with variable malignant potential. These tumors that currently accepted nomenclature are benign, borderline and malignant according to the World Health Organization. It tends to behave in a benign way but it may undergo a malignant transformation. The purpose of this study was to present our Case load of phyllodes tumor, and evalu...