In past decades, catalytic cross-coupling reactions between organic halides and organometallic reagents to construct carbon-carbon bond have achieved a tremendous progress. However, organolithium reagents have rarely been used in cross-coupling reactions, due mainly to their high reactivity. Another limitation of this transformation using organolithium reagents is how to control reactivity with...

1,4-Diazabicyclo[2.2.2]octane (DABCO) has been evaluated as a starting material for the synthesis of 1-alkyl-4-(2-phenoxyethyl)piperazines and related derivatives. We found that 1-alkyl-1,4-diazabicyclo[2.2.2]octan-1-ium salts, resulting from the alkylation of DABCO, efficiently react with a variety of nucleophiles in polyethyleneglycol (PEG) or diglyme at high temperatures to give piperazine p...

A number of N-arylmethyl substituted indole derivatives have been synthesized and their effectiveness against ADP and arachidonic acid induced platelet aggregation in human plasma was determined. The desired compounds were synthesized by reacting the appropriate aniline derivative with isatin (or substituted isatin) to form the corresponding imine structures. The so formed compound was then act...

Pentaphosphaferrocenes [CpR Fe(η5 -P5 )] (1) and CuI halides are excellent building blocks for the formation of discrete supramolecules. Herein, we demonstrate the potential of Cu(CF3 SO3 ) for the construction of the novel 2D polymer [{Cp*Fe(μ4 ,η5:1:1:1 -P5 )}{Cu(CF3 SO3 )}]n (2) and the unprecedented nanosphere (CH2 Cl2 )1.4 @[{CpBn Fe(η5 -P5 )}12 {Cu(CF3 SO3 )}19.6 ] (3). The supramolecule ...

Z. Naturforsch. 56 b, 57-61 (2001); received September 11, 2000 Organic-Inorganic Hybrids, Low-Dimensional Semiconductors, Fluorescence Using 1-chlorodecane (C10H21CI), benzyl chloride (C6H5CH2CI), a,a'-dichloro-p-xylene (CICH2C6H4CH2CI), 4-phenylbenzyl chloride (C6H5C6H4CH2CI), 2-bromomethyl-naphthalene (CioHyC^Br), 4-bromomethyl-7-methoxycoumarin (CioHzO^C^Br), 2-bromomethylanthraquinone (CuH...

The spectral moments of the edge adjacency matrix recently have been successfully employed in quantitative structure-property relationship (QSPR) and quantitative structure-activity relationship (QSAR) studies of alkanes, alkyl halides, benzyl alcohols, and cycloalkanes.1-3 In this work we examined spectral moments of the edge adjacency matrix of benzenoid hydrocarbons. We designed combinatoria...

In past decades, catalytic cross-coupling reactions between organic halides and organometallic reagents to construct carbon–carbon bond have achieved a tremendous progress. However, organolithium reagents have rarely been used in cross-coupling reactions, due mainly to their high reactivity. Another limitation of this transformation using organolithium reagents is how to control reactivity with...

The present work highlights the synthesis and effect of introducing substituents on nitrogen at position -1 five 2-benzylthiopyrimidine derivatives (6a-e). compounds (6a-e) were obtained by condensation 2-thiopyrimidines (4) with benzyl halides in presence a base. As for N-alkylated/arylated-2thiobenzylpyrimidines (8a-k), they nucleophilic substitution reaction basic medium. All synthesized cha...