A 60-year-old female with Bernard-Soulier and Hemophilia presented to the Emergency Department epistaxis for three days. Despite an extended hospital admission pharmacological, manual, surgical interventions, she failed achieve hemostasis was discharged a nursing facility under hospice care. This case report explores challenges of managing patient chronic complicated by multiple hematologic dis...

The molecular nature of platelet receptors for quinineand quinidine-dependent antiplatelet antibodies (Q.Ab and Qd.Ab) was studied by immunoblotting. One Q.Ab caused quinine-dependent lgG binding to platelet proteins with molecular weights (mol wts) of 1 74 Kd and 93 Kd and another to only a 93-Kd protein. A third Q.Ab caused binding to 1 74-. 140-. 93-. and 57-Kd proteins, while a fourth Q.Ab ...

Platelets play a critical role in hemostasis and are involved in wound repair and inflammatory processes. Contact to the subendothelial matrix induces platelet activation that is followed by release of cytokines and growth factors and formation of a vascular plug. Several inherited defects of platelet function resulting in bleeding diathesis are known. However, only in the minority of these dis...

Contamination of Enterocytozoon bieneusi Desportes, Charpentier, Galian, Bernard, Cochand-Priollet, Laverne, Ravisse, et Modigliani, 1985 in water sources may cause outbreaks of microsporidiosis. To examine the occurrence of E. bieneusi, 108 raw wastewater samples were collected from three wastewater treated plants in Zhengzhou, China. In total, 46 samples were PCR positive for E. bieneusi. A t...