background: thalassemia represents a serious health problem in iran because of its heterogeneous frequency and the existing endogamy system. it is an inherited blood disease characterized by the under production of normal hemoglobin, the oxygen-carrying protein in red blood cells. materials and methods: in this study, serum antioxidants including selenium (se), zinc (zn) and copper (cu) were me...

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background we aimed to investigate the frequency of celiac disease in children with β-thalassemia major (b-tm) in shiraz, southern iran. materials and methods in this study, the prevalence of celiac disease in children with b-tm was evaluated. children with btm were screened for celiac disease by ant-tissue transglutaminase (anti-ttg) iga antibody, iga level and anti-ttg igg. a total of 1500 sc...

dear editor, the problem of congenital hemoglobin disorder is common in tropical asia. in tropical southeast asian countries, very high prevalence of thalassemia disorder especially for beta thalassemia is observed. this tropical hematological problem affects millions of population and cause several health disorders. of interest, the issue of reproductive health impairment of the population wit...

clostridium perfringens is a gram-positive, obligate anaerobic bacterium, which is widely distributed in the environment. c. perfringens is subdivided to 5 groups (types a to e), based on its four major toxin (alpha, beta, epsilon and iota). c. perfringens type b beta toxin causes inflammation and bloody necrotic enteritis. type b related enterotoxaemia is a major problem of veterinary sciences...

Background and Aims: Leishmaniasis is an intracellular protozoan- parasitic disease, the common vector of transmission. Both zoonotic and anthroponotic cutaneous leishmaniasis (CL) are endemic in different foci. With regard to the cutaneous form, 1.0-1.5 million cases were reported annually with 90% of the cases. Although antimony-containing compounds that are the main drugs used to treat Leish...

introduction: zinc has a significant positive effect on the immune system and physical development in human beings. many investigators believe that the level of plasma zinc in thalasemic patients is reduced firstly because of receiving chelators like desferoxamin, and secondly because of impairment of some organs like kidney, liver, thyroid and hypophysis. therefore this study was carried out t...

INTRODUCTION Our information about renal involvement in beta-thalassemia major is limited. Recently, few studies have reported proteinuria, hypercalcuria, phosphaturia, and oversecretion of tubular damage markers; however, hematuria has not yet been meticulously studied in these patients. We investigated hematuria in patients with beta-thalassemia major. MATERIALS AND METHODS Urinalysis was p...