mirizzi’s syndrome is a rare complication of gallstone disease , that gallbladder lumen can lie alongside the common hepatic duct, resulting in inflamation and resultan bile duct stricture . most cases are not indentified preoperatively. variations of the cystic duct and its point of :union: with the common hepatic duct are surgically important . here, we present an unusual case of type i miriz...

Background and Aim: Bile duct injuries (BDIs) are complex complications developed during laparoscopic cholecystectomy leading to the postoperative morbidity mortality. Auxiliary bile injury, vascular structures injuries, portal vein, cyst leakage damage right hepatic artery caused by injuries. The purpose of present study was investigate incidence, clinical presentation, treatment modality chol...

Plasminogen activator inhibitor-1 (PAI-1) is an acute phase protein known to correlate with hepatic fibrosis. However, whether or not PAI-1 plays a causal role in this disease process had not been directly tested. Therefore, wild-type or PAI-1 knockout (PAI-1(-/-)) mice underwent bile duct ligation. Mice were sacrificed either 3 or 14 days after surgery for assessment of early (i.e., inflammati...

Objective: The main objective was to determine the complications of laparoscopic cholecystectomy (LC) and its causes at Isra University Hospital, Hyderabad. Methodology: This was a retrospective study carried out from July 2005 to June 2007. Data of all patients undergoing laparoscopic cholecystectomy during the study period and fulfilling the selection criteria was collected and analyzed retro...

Bile ducts play a crucial role in the formation and secretion of bile as well as excretion of circulating xenobiotic substances. In addition to its secretory and excretory functions, bile duct epithelium plays an important role in the formation of a barrier to the diffusion of toxic substances from bile into the hepatic interstitial tissue. Disruption of barrier function and toxic injury to liv...