At one time it was thought that biliary epithelial cells simply formed the lining to the tubular conduits which constitute the biliary tract. Development of in vitro systems for culturing biliary epithelial cells has enabled functional studies which increasingly show that this is far from true, and that biliary epithelial cells do have important functional roles. Disruption of these functions m...

BACKGROUND Cholangiocarcinoma is an aggressive tumor with a tendency for local invasion and distant metastases. Timely diagnosis is very important because surgical resection (R0) remains the only hope for a cure. However, at present, there is no available tumor marker that can differentiate cholangiocarcinoma from benign bile duct disease. Previous studies have demonstrated that matrix metallop...

Gallbladder carcinomas are the most common malignancy of biliary tract. Since it does not have specific signs and symptoms, is mostly detected during cholecystectomy for gallstones. In this direction, we also found dysplasia in 74 530 patients included our study, gallbladder carcinoma 3 patients, order to show frequency who underwent due benign diseases. This very important catching cancers at ...

The incidence of gallstone disease (GSD) and metabolic syndrome (MS) is increasing every year. ICD-10 does not have the diagnosis “metabolic syndrome” it has been coded on basis diseases despite its wide prevalence now. These are multifactorial diseases, pathogenesis which intertwined mutually aggravate their courses. There both external internal reasons forming stones in biliary tract. Genetic...

BACKGROUND To determine the most common abnormal anatomical variations of extra-hepatic biliary tract (EHBT), and their relation to biliary tract injuries and stones formation. METHODS This is a retrospective review of 120 patients, who underwent endoscopic retrograde cholangiopancreaticography (ERCP) and/or magnetic resonance cholangiopancreaticography (MRCP), between July 2011 and June 2013...