نتایج جستجو برای: binding effects

تعداد نتایج: 1912460  

Journal: :biomacromolecular journal 2015
fahimeh mehranfar abdol-khalegh bordbar razieh amiri amiri

curcumin (cur) is the active curcuminoid with many physiological, biochemical, and pharmacological properties. solubility and stability of cur is the limiting factors for realizing its therapeutic potential. bovine β-casein is an abundant milk protein that is highly amphiphilic and self-assembles into stable micellar nanoparticles in aqueous solution. β-casein nanoparticle can solubilize cur mo...

2008
Alan Dix Masitah Ghazali Steve Gill Joanna Hare Devina Ramduny-Ellis

This paper explores the formal specification of the physical behaviour of devices “unplugged” from their digital effects. By doing this we seek to better understand the nature of physical interaction and the way this can be exploited to improve the design of hybrid devices with both physical and digital features. We use modified state transition networks of the physical behaviour, which we call...

Journal: :iranian journal of allergy, asthma and immunology 0
sara zahedifard immunology, asthma and allergy research institute, tehran university of medical sciences, tehran, iran. elahe rashidi immunology, asthma and allergy research institute, tehran university of medical sciences, tehran, iran. sedigheh shams department of pathology, children hospital medical center, tehran university of medical sciences, tehran, iran. shiva saghafi immunology, asthma and allergy research institute, tehran university of medical sciences, tehran, iran. mohammadreza fazlollahi immunology, asthma and allergy research institute, tehran university of medical sciences, tehran, iran. azadeh talebzadeh immunology, asthma and allergy research institute, tehran university of medical sciences, tehran, iran.

mannan-binding lectin (mbl) is a vital protein of innate immune system and has two critical functions: complement activation through the lectin pathway and opsonization. mbl deficiency has been classified as the most common inherited immunodeficiency known in humans (about 30% of the population), and is associated with predisposition to infections and high risk of some autoimmune diseases. the ...

Journal: :bulletin of emergency and trauma 0
ali mehrshad department of clinical sciences, faculty of veterinary medicine, urmia branch, islamic azad university, urmia, iran ashkan seddighnia department of basic sciences, faculty of veterinary medicine, urmia branch, islamic azad university, urmia, iran mohammadreza shadabi department of basic sciences, faculty of veterinary medicine, urmia branch, islamic azad university, urmia, iran alireza najafpour department of basic sciences, faculty of veterinary medicine, urmia branch, islamic azad university, urmia, iran rahim mohammadi department of internal medicine and clinical pathology, faculty of veterinary medicine, urmia university, urmia, iran.

objective: to assess the effect of heparin binding neurotrophic factor (hbnf) on sciatic nerve regeneration in animal model of rat. methods: seventy-five male wistar rats were divided into five experimental groups randomly (each group containing 15 animals): sham operation group (sham), autograft group (auto), transected control (tc), chitosan conduit (chit) and heparin binding neurotrophic fac...

Journal: :iranian journal of veterinary research 2012
f. bagherzadeh kasmani m.a. karimi torshizi a.a. allameh f. shariatmadari

this study was carried out to examine aflatoxin b1 (afb1) removal ability of four strains of lactic acidbacteria (lab). three indigenous (lactobacillus rhamnosus tmu094, lactobacillus fermentum tmu121and pedioccus pentosaceus tmu457) and a non-indigenous (labacillus rhamnosus ptcc1637) isolateswere studied. the strains were incubated with (afb1) at different time. the toxin residual in the supe...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1978
R Walter J M van Ree D de Wied

Vasopressin and other neurohypophyseal peptides affect various processes related to memory and/or learning. A single subcutaneous injection of vasopressin increases resistance to extinction of a pole-jumping avoidance response in rat. This test system has been applied in an attempt to relate structural aspects of neurohypophyseal peptides, analogues, and derivatives with truncated sequences to ...

2012
Youngjo Lee

We present the frailtyHL package for fitting semi-parametric frailty models using hlikelihood. This package allows lognormal or gamma frailties for random-effect distribution, and it fits shared or multilevel frailty models for correlated survival data. Functions are provided to format and summarize the frailtyHL results. The estimates of fixed effects and frailty parameters and their standard ...

Journal: :FEBS Journal 2021

G protein-coupled receptors (GPCRs) are essential cell membrane signaling molecules and represent the most important class of drug targets. Some pathways downstream a GPCR may be responsible for adverse effects, while others mediate therapeutic efficacy. Biased ligands preferentially activate only subset all pathways. They hold great potential to become next-generation drugs with less side effe...

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