Bone defects caused by trauma or pathological events are major clinical and socioeconomic burdens. Thus, the efforts of regenerative medicine have been focused on the development of non-biodegradable materials resembling bone features. Consequently, the use of bioactive glass as a promising alternative to inert graft materials has been proposed. Bioactive glass is a synthetic silica-based mater...

Objective: The rough surfaces of removable appliances used in pediatric dentistry or orthodontics, may result inan environment for biofilm accumulation, yielding to enamel demineralization. This study aimed assess theeffects adding nanoparticles bioactive glass polymethylmethacrylate promote the antibacterial activityin acrylic resins. Material and Methods: Acrylic resin specimens (20x20x1mm3) ...

Objective(s): The aim of this study was to synthesis new dental nanocomposites reinforced with fabricated glass nanoparticles and compare two methods for fabrication and investigate the effect of this filler on mechanical properties. Materials and Methods: The glass nanoparticles were produced by wet milling process. The particle size and shape was achieved using PSA and SEM. Glass nanoparticle...

BACKGROUND Mastoid obliteration seeks to replace an open mastoid cavity with material that will become viable and free of infection and cholesteatoma. The purpose of this study was to evaluate the efficacy of bioactive glass ceramic particles for mastoid obliteration using a guinea pig animal model. MATERIALS AND METHODS Ten male guinea pigs (weighing 250-300 g) with normal eardrums and Preye...

A new melted bioactive system containing gold nanoparticles (AuNPs) was prepared exploiting a post-synthesis thermal treatment that allows one to modify crystal phases and nature, shape and distribution of the gold species in the glass-ceramic matrix as evidenced by UV-visible spectroscopy, transmission electron microscopy and powder X-ray diffraction analysis. In human MG-63 osteoblasts the pr...

Composite nanofibers composed of polyacrylonitrile (PAN)-based carbon nanofibers and bioactive glass (BG) nanoparticles have been prepared by electrospinning and in situ sintering. Morphology observation showed that the BG nanoparticles of size 20-50 nm were uniformly distributed on the surface of composite nanofibers with 350 nm average diameter after carbonization. Biological mineralization i...

Biomedical polymer-silicate nanocomposites have potential to become critically important to the development of biomedical applications, ranging from diagnostic and therapeutic devices, tissue regeneration and drug delivery matrixes to various biotechnologies that are inspired by biology but have only indirect biomedical relation. The fundamental understanding of polymer-nanoparticle interaction...