INTRODUCTION Vaccine strategies represent an essential component for the future control of schistosomiasis. This work aimed to evaluate the role of detergents for potentiating the effect of Schistosoma mansoni tegumental antigens (TA) against challenge infection. METHODOLOGY Two detergents; Triton X-100 (TX-100) and sodium dodecyl sulfate (SDS), were selected for extraction of tegumental prot...

Washing clothes is an activity that often done by people in the world. However, detergents sold market are harmful to human skin and aquatic ecosystems rivers. Therefore, this research focuses on environmentally friendly can minimize impact environment humans. This study aims develop standard operating procedures (SOP) production of detergents. was conducted developing initial SOP design, simul...

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy CADASIL is caused by more than a hundred NOTCH3 mutations. Virtually all encoded mutant proteins contain an odd number of cysteines. As such, structural changes in NOTCH3 may be the primary molecular abnormality in CADASIL. Thus, we sought evidence for structurally altered NOTCH3 protein in CADASIL tissue...

concept argue that from 9 to 23 percent of the cellular metabolic energy is required for the operation of the sodium pump (3). The question is, then, whether the cell can provide the energy necessary to pump potassium, calcium, magnesium, sugars, and amino acids if it takes 10 percent of the energy to run only one pump? Recently, some alternative hypotheses, often referred to, in general, as th...

In clinical dermatology, few questions are asked more commonly than “What is the best way for me to clean my skin or hair?” The modern dermatologist needs to be familiar with the physiologic action of cleansing products available on the market. This familiarity should include chemical composition, application, cosmetic benefits, and safety, as well as potential hazards. This knowledge must be a...

Generating stable conditions for membrane proteins after extraction from their lipid bilayer environment is essential for subsequent characterization. Detergents are the most widely used means to obtain this stable environment; however, different types of membrane proteins have been found to require detergents with varying properties for optimal extraction efficiency and stability after extract...

Amylases are key enzymes in the processing of starch many kingdoms life. They important catalysts industrial biotechnology where they applied in, among others, food and production detergents. In man amylases first digestion to glucose arguably also preferred target therapeutic strategies aimed at treatment type 2 diabetes patients through down-tuning assimilation. Efficient sensitive assays tha...