OBJECTIVE The existing methods for identifying multiple rare variants underlying complex diseases in family samples are underpowered. Therefore, we aim to develop a new set-based method for an association study of dichotomous traits in family samples. METHODS We introduce a framework for testing the association of genetic variants with diseases in family samples based on a generalized linear ...

Genetic diversity among plants sprouted from seven year old clones of mulberry (Morus indica var. S36) was studied using molecular markers such as ISSR and RAPD. The clones showed significant variability in sex expression and the sprouting behavior. These changes were appeared after seven years of rigorous pruning and training (pruned once in every 3-4months). Genetic diversity analysis reveale...

genetic diversity among plants sprouted from seven year old clones of mulberry (morus indica var. s36) was studied using molecular markers such as issr and rapd. the clones showed significant variability in sex expression and the sprouting behavior. these changes were appeared after seven years of rigorous pruning and training (pruned once in every 3-4months). genetic diversity analysis reveale...

Regulation of microRNA (miRNA) expression contributes to a wide range of target gene expression and phenotypes. The miRNA expression in the liver, the central metabolic organ, was examined in 209 pigs, and integrated with haematological and clinical biomarkers of metabolic and overall health, mRNA-target expression levels and single-nucleotide polymorphism (SNP) genotypes. The expression levels...

Abstract Poor color stability limits meat shelf life, and poses an economic challenge to processors retailers, contributes food waste. The US pork industry has only a limited understanding of fresh discoloration, with most inferences about discolored being extrapolated from beef discoloration studies. Despite substantial research into consumer perception, biochemical mechanisms, impact little i...