Abstract Background Psoriasis is a cutaneous inflammatory disorder with associated comorbidities which can influence treatment options. Biologics are immune‐modifying agents that improve or worsen pre‐existing psoriasis comorbidities. The risks particular biologic agent and its effects on comorbidity guide decisions direct further workup to screen for markers of these Methods A literature searc...

introduction: complicated crown- root fractures, extended caries and iatrogenic destruction often result in insufficient sound tooth structures and compromise the biologic width. two common options for re-establishing flap with osseous surgery. although some advantages are related to these two options, but coronal movement of gingival and alveolar bone in orthodontic extrusion, esthetic problem...

BACKGROUND Multiple marker accumulation impacts tumor progression and biologic phenotypes affect clinical outcome of patients with head and neck cancer. Hence, this study investigated a battery of molecular markers that may help to reflect biologic aggressiveness and predict prognosis. METHODS Epidermal growth factor receptor (EGFR), Stat3, H-ras, c-myc, p53, cyclin D1, p16, Rb, Ki-67, and Bc...

The impact of toxins on the developing brain is usually subtle for an individual child, but the damage can be substantial at the population level. Numerous challenges must be addressed to definitively test the impact of toxins on brain development in children: We must quantify exposure using a biologic marker or pollutant; account for an ever-expanding set of potential confounders; identify cri...

1. Abstract 2. Introduction 2.1. The Normal Liver 2.2. Biochemical evaluation hepatic function 2.2.1. Markers of synthetic function 2.2.2. Markers of excretory function 2.2.3. Markers of hepatocellualr damage 2.3. Liver Failure 2.3.1. Coagulopathy 2.3.2. Hepatic encephalopathy and cerebral edema 2.4. Current treatment for liver failure 3. Non-biologic systems 3.1. Hemodialysis 3.2. High-volume ...

Most Schistosoma mansoni infections are egg-negative after a single dose of oxamniquine. A cohort of 661 infected children was treated at 6-month intervals and assessed for nutritional and parasitological status. Initial biochemical and immunologic markers were measured in a subset of 84 children. All were treated at the start of therapy and at 6 months. Immunoglobulins only served as markers f...

Identifying leads and lags between high- and low-latitude abrupt climate shifts is needed to understand where and how such events were triggered. Vascular plant biomarkers preserved in Cariaco basin sediments reveal rapid vegetation changes in northern South America during the last deglaciation, 15,000 to 10,000 years ago. Comparing the biomarker records to climate proxies from the same sedimen...