Cells can perceive complex mechanical cues across both the micro- and nanoscale which influence their development. While causative effects between surface topography cellular function be demonstrated, variability in materials used this screening process makes it difficult to discern whether observed phenotypic changes are indeed a result of topographical alone or inherent difference material pr...

Petri Nets (PNs) and their extensions are promising methods for modeling and simulating biological systems. We surveyed PN formalisms and tools and compared them based on their mathematical capabilities as well as by their appropriateness to represent typical biological processes. We measured the ability of these tools to model specific features of biological systems and answer a set of biologi...