نتایج جستجو برای: bioprobes
تعداد نتایج: 148 فیلتر نتایج به سال:
Organic interfacial compounds (OICs) are required as linkers for the highly stable and efficient immobilization of bioprobes in nanobiosensors using 2D nanomaterials such graphene. Herein, we first demonstrated fabrication a field-effect transistor (FET) via microelectromechanical system process after covalent functionalization on large-scale graphene by introducing oligo(phenylene-ethynylene)a...
Activity-based approaches for designing AIEgens possess prominent advantages including high selectivity, sensitivity, and signal-to-noise ratio, they have received more attention in recent years. Excellent activatable AIE probes been reported detecting toxic substances, imaging intracellular active molecules/biomolecules, as well monitoring the activity of overexpressed enzymes cancers. Moreove...
Purpose. The aim of this paper is to develop new optical bioprobes for the imaging of apoptosis. Procedure. We developed quenched near-infrared probes which become fluorescent upon cleavage by caspase-3, the key regulatory enzyme of apoptosis. Results. Probes were shown to be selectively cleaved by recombinant caspase-3. Apoptosis of cultured endothelial cells was associated with an increased f...
Supporting Information Naked Eye Detection of Multiple Tumor-Related mRNAs from Patients with Photonic-Crystal Micropattern Supported Dual-Modal Upconversion Bioprobes Xiaoxia Hua, Yingqian Wanga, Haoyang Liua, Jie Wanga, Yaning Tana, Fubing Wangb, Quan Yuan*,a, and Weihong Tanc,d aKey Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and ...
BACKGROUND Fluorescence and bioluminescence resonance energy transfer (F/BRET) are two forms of Förster resonance energy transfer, which can be used for optical transduction of biosensors. BRET has several advantages over fluorescence-based technologies because it does not require an external light source. There would be benefits in combining BRET transduction with microfluidics but the low lum...
The in-situ fluorescence triggering of bioprobes only using endogenous bioforces is an ideal non-destructive real-time detection method, which particular interest to improve the accuracy clinical diagnosis and treatment. We have recently reported a strategy spiropyran switching triggered by biological forces in vivo develop optical probes for this purpose. However, such probes, as with all spir...
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