Rapid diagnosis of diseases at their initial stage is critical for effective clinical outcomes and promotes general public health. Classical in vitro diagnostics require centralized laboratories, tedious work and large, expensive devices. In recent years, numerous electrochemical biosensors have been developed and proposed for detection of various diseases based on specific biomarkers taking ad...

Because of the need in medical diagnostics and more recently, the worldwide concern of the threat of chemical and bioterrorism great demand of bio-intelligence arises. Here, the review of biosensors technology with specific concentration on optical biosensors is provided. Remarkable developments have been reported in the last few years in the field of optical biosensors. Optical biosensors util...

This review (with 35 references) summarizes the various strategies used in biosensors for galactose, and their analytical performance. A brief comparison of the enzyme immobilization methods employed and the analytical performance characteristics of a range of galactose biosensors are first summarized in tabular form and then described in detail. Selected examples have been included to demonstr...

Biosensors for small molecules can be used in applications that range from metabolic engineering to orthogonal control of transcription. Here, we produce biosensors based on a ligand-binding domain (LBD) by using a method that, in principle, can be applied to any target molecule. The LBD is fused to either a fluorescent protein or a transcriptional activator and is destabilized by mutation such...

The applications of biosensors range from environmental testing and biowarfare agent detection to clinical testing and cell analysis. In recent years, biosensors have become increasingly prevalent in clinical testing and point-of-care testing. This is driven in part by the desire to decrease the cost of health care, to shift some of the analytical tests from centralized facilities to "frontline...

A biosensor is an analytical device which integrates a biological recognition element with a physical transducer to generate a measurable signal proportional to the concentration of the analyses. A microbial biosensor consists of a transducer in conjunction with immobilized viable or non-viable microbial cells. Non-viable cells obtained after Permeable or whole cells containing periplasmic enzy...

The importance of nanotechnology in medical technologies, especially biomedical diagnostics, is indubitable. By taking advantages of nanomaterials, many medical diagnostics methods have been developed so far, including electrochemical nanobiosensors. They have been used for quantification of different clinical biomarkers for detecting, screening, or follow up a disease. microRNAs (miRNAs) are o...

for centuries, herbal drugs have been the only accessible resource for treatment of pain and passions. today, despite remarkable progress and development of synthetic drugs, medicinal plants and their derived drugs are used massively. so that, in some countries medicinal plants is inseparable from drugs and treatment systems. more ever, their marketing and economical aspects are more flourishin...