نتایج جستجو برای: blaschko lines
تعداد نتایج: 217319 فیلتر نتایج به سال:
Linear porokeratosis is a rare variant. It can be present at birth or can develop in adult life. Lesions of linear porokeratosis are grouped and linearly arranged along the lines of Blaschko. On the extremities it affects the distal portion more than the proximal areas. On the trunk these can be zosteriform in distribution. Lesions of linear porokeratosis probably result from an abnormal clone ...
Hypomelanosis of Ito-A Case of Pigmentary Mosaicism Associated with Partial Trisomy of Chromosome 20
Introduction: Hypomelanosis of Ito is characterized by hypopigmentation along the lines of Blaschko, evident at birth or during childhood, in combination with variable extra cutaneous findings, mainly affecting the central nervous system, musculoskeletal system and eyes. Most common lyis caused by chromosomal mosaicism associated with a variety of changes in structure or number of autosomes or ...
Eruptions similar to those of lichen planus (LP) are associated with systemic diseases or have been induced by many drugs. Linear lesions as a Koebner effect are frequently found in LP but isolated long, narrow, linear lesions, which may extend the whole length of the limb, are rare though rather more common in childhood. Some cases of zonal or zosteriform LP have been described in the literatu...
Actas Dermosifiliogr. 2009;100:151-62 157 4. Libow LF, Coots NV. Lichen sclerosus following the lines of Blaschko. J Am Acad Dermatol. 1998;38:831-3. 5. Okamoto H, Mizuno K, Ohkuwa T. Unilateral linear lichen sclerosus et atrophicus. Eur J Dermatol. 1998;8:575-7. 6. Choi SW, Yang JE, Park HJ, Kim CW. A case of extragenital lichen sclerosus following Blaschko’s lines. J Am Acad Dermatol. 2000;43...
Lichens striatus (LS) is an acquired, self-limiting inflammatory dermatosis that follows the lines of Blaschko. The etiology of the eruption is unknown, but several theories have been proposed with focus on environmental factors, viral infection, cutaneous injury, hypersensitivity, and genetic predisposition. We describe a 19-year-old woman who developed a unilateral linear eruption 17 months a...
Sir, Incontinentia pigmenti (IP) is an X-linked dominant trait that is intrauterine lethal for males. The disorder is caused by NEMO mutations involving the NFkB activation pathway (1). It is characterized by linear skin lesions and various defects of the central nervous system, the teeth and the eyes. The cutaneous lesions are arranged along the lines of Blaschko, reflecting functional X-chrom...
A patient is reported with mental retardation, facial and body asymmetry, and hyperpigmented areas limited to the right side of the body. Cytogenetic studies revealed trisomy 18 in 50% of peripheral blood lymphocytes; fibroblast cultures from the hyperpigmented area showed pure trisomy 18, while the karyotype on the unaffected side was normal. This could be an example of the 'lines of Blaschko'...
A 52-year-old woman presented with a 10-year-history of memory loss and executive dysfunction. Examination disclosed hypopigmented whorls and linear streaks following the lines of Blaschko in different body segments (Figure 1), typical of Hypomelanosis of Ito (HI). Brain MRI showed marked enlarged Virchow-Robin spaces (Figure 2). HI or incontinentia pigmenti achromians (MIM#300337) represents a...
Sir, Linear and whorled nevoid hypermelanosis (LWNH) is characterized by hyperpigmented macules in a streaky configuration along the lines of Blaschko, without preceding inflammation or atrophy.[1-3] Lesions are distributed mainly on the trunk and extremities, sparing palms, soles, and mucosae. The usual age of the onset of hyperpigmentation occurs within the first few weeks of life, continues ...
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