aneurysms of gastric vessels (dieulafoy`s disease, caliber-persistent artery) are thought to be of malformative rather than degenerative origin. they are usually single, located in the submucosa, usually on the lesser curvature, and characterized by a large tortuous vessel surmounted by a small defect in the overlying mucosa. when the lesion perforates, massive and sometimes fatal hemorrhage ma...

AIM Oral anticoagulants are the most common used substance for treatment and prophylaxis of warfarin venous and arterial thromboembolic disorders in the world. Therapeutic index of warfarin is narrow. CYP2C9 is a hepatic microsomal enzyme and has a primary role in metabolism of warfarin and genetic variations of CYP2C9 may cause a serious effect on the response to warfarin in patients. The aim ...

background rhinoplasty is one of the most common surgeries of the plastic surgery and as well as ear, throat and nose. intra-operative bleeding during surgery is one of the most important factors that may impair the surgeon’s job. providing a clean blood-free surgical filed makes the operation faster, easier and with a better quality. one way to achieve this goal is to induce hypotension. this ...

introduction: post cardiac surgery hemorrhagic syndromes, potentialized by implementing   cardiopulmonary bypass, leads to increased hazards of blood products transfusion and          pertains serious impacts on immediate patients outcome. the objective of this clinical trial was to investigate the efficiency of exogenous fibrinogen to control hemorrhagic syndromes following cardiac surgery in ...

statement of the problem patients with chronic renal failure undergoing hemodialysis are affected by many systemic diseases due to their lack of ability to control water and electrolyte balance and filtrate waste products. obviously, there would be some manifestations in the oral cavity especially in the gingiva. purpose this study was carried out to survey the prevalence of periodontal disease...

a 50-year-old lady presented with bloody vomiting and melena since four days prior to admission. her medical history was significant only for hypertension which was controlled by a 5 mg daily dose of amlodipine. she occasionally took nsaids. on admission, the physical exam revealed only mild tachycardia and pallor. hemoglobin was 9.7 g/dl, which subsequently declined to 7.9 g/dl. the first uppe...

BACKGROUND A new polysaccharide hemostatic system (EndoClot(TM) ) was recently developed for bleeding control in gastrointestinal tract endoscopy; however, its efficacy and safety is not yet well established in colorectal endoscopic mucosal resection (EMR). The aim of the present study was to observe the bleeding control effect after EMR in the colorectum. PATIENTS AND METHODS EndoClot(TM) wa...

OBJECTIVE To describe patterns of vaginal bleeding in the first 20 weeks of pregnancy and evaluate the association between patterns of bleeding and risk of subsequent pre-eclampsia in nulliparous women. DESIGN Cohort study. SETTING Participating centres of the Screening for Pregnancy Endpoints (SCOPE) study in Auckland (New Zealand), Adelaide (Australia), Manchester and London (UK) and Cork...