The serotonergic deficits induced by 3,4-methylenedioxyethamphetamine (MDEA, "eve"), were examined and compared with 3,4 methylenedioxymethamphetamine (MDMA, "ecstasy"). A single dose of MDEA (10, 20, or 40 mg/kg IP) induced a dose-related hyperthermia, but only the highest dose significantly reduced 5-HT content and 5-HT transporter density in the frontal cortex and in the hippocampus 7 days l...

Context The CO2CRC is involved in research, development and demonstration of a number of different methods for the large scale capture of carbon dioxide. The Engineering Development Group within the CO2CRC is involved with assessing and optimization the process designs associated with the capture of CO2. The Engineering Development Group recently assessed a number of capture methods for air blo...

UNLABELLED Amiodarone (AMI) is a potent antiarrhythmic drug, but its metabolism has not yet been fully documented. Mono-N-desethylamiodarone (MDEA) is its only known metabolite. Our preliminary investigations using rabbit liver microsomes had shown that in vitro AMI was biotransformed to MDEA, and the latter was rapidly further biodegraded to other unknown products. The aim of the present study...

We have recently shown that methylenedioxymethamphetamine (MDMA), methylenedioxyamphetamine (MDA), cathinone and methylenedioxyethylamphetamine (MDEA) have a cocaine-like action to potentiate the contractile actions of noradrenaline but not isoprenaline in the 1-Hz paced rat right ventricle. The purpose of this study was to directly test the actions of these compounds at the noradrenaline trans...

Using solid phase extraction (SPE) combined with HPLCfluorescence/photodiode array (PDA) detection several low molecular-weight alkylamines (including ethylamine and propylamine) have been detected in the gas-phase, released during the oxidative/thermal degradation of monoethanolamine (MEA), an amine-based postcombustion CO2 capture solvent. In this study, a 30 wt% aqueous MEA solution was degr...

The solubility of CO2 in various aqueous amine based solvents was determined at lower CO2 partial pressures. Cyclic capacity of various potential aqueous amine based solvents at 10 kPa CO2 partial pressure was determined by performing CO2 absorption at 30C, regeneration at 90C and at 1 atmosphere. 1,7-Diaminoheptane and 1,6Hexanediamine, N,N'-dimethyl was found to be having high cyclic loading ...

Aqueous biphasic systems were investigated for the production of formate-amine adducts by metal-catalyzed CO2 hydrogenation, including typical scrubbing solutions as feedstocks. Different hydrophobic organic solvents and ionic liquids could be employed as the stationary phase for cis-[Ru(dppm)2 Cl2 ] (dppm=bis-diphenylphosphinomethane) as prototypical catalyst without any modification or taggin...

Mutants of Aspergillus nidulans resistant to methylammonium toxicity are simultaneously derepressed in the presence of ammonium for apparently all ammonium-repressible activities. Enzyme assays directly demonstrate derepression of nitrate, nitrite, and hydroxylamine reductases, xanthine dehydrogenase, urate oxidase, and allantoinase, whereas in vivo tests show that ammonium and methylammonium r...