Cardiac PET imaging using 13N-ammonia and 18FDG was performed on 17 normal volunteers in the glucose-loaded and fasted states. PET images (glucose-loaded and fasted) were subjected to qualitative visual analysis using the descriptors: image quality, FDG blood-pool activity, ammonia lung field activity, and clinical interpretability. Glucose-loaded studies had better image quality, diminished FD...

Introduction: Delayed enhancement using segmented inversion recovery (IR) TurboFLASH imaging is the clinical gold standard for identifying myocardial infarction. It is also clinically used for assessment of non-ischemic cardiomyopathy [1]. Although this technique allows high contrast between infarct/infiltrate and normal myocardium, it is limited in its evaluation of the subendocardium because ...

we report a three-phase bone scintigraphy for the diagnosis of a peripheral bone lesion caused by systemic sarcoidosis. a 32-year-old man with suspected osteomyelitis of the right forefinger underwent three-phase bone scintigraphy with tc-99m hydroxymethylene diphosphonate (hmdp) and single-photon emission computed tomography/computed tomography (spect/ct). the lesion was rich in blood flow acc...

The determination of blood \'olume of a group of normal adult subjects, including both men and women, has been carried out using low doses of Jl31_ labelled human serum albumin, about O.O? jlc per kg of body weight. Further, a successive test was carried out using small doses of p32-tagged red blood cells, about 0.01 jlc per kg of body weight. These doses are at least 10 times less than the nor...

This is the first study of the intravascular iron oxide particle contrast agent, NC100150 Injection (Nycomed Imaging AS, Oslo, Norway, a part of Nycomed Amersham) in magnetic resonance imaging of the human heart. Eighteen healthy male volunteers were studied at both 0.5 and 1.5 T before and after the administration of NC100150 Injection. Transaxial spin-echo images were acquired at both field s...

PURPOSE To assess the degree and regional pattern of first-pass brain enhancement using dynamic MR imaging. MATERIALS AND METHODS Ultrafast MR imaging (1.06-second acquisition time per image) was performed in 19 healthy subjects following a bolus IV injection of a gadolinium contrast agent; 36 patients with suspected pathology were studied using the same protocol. RESULTS Calculated percent...

We synthesized PYY-(1-36) (nonselective between Y(1) and Y(2) receptor subtype agonists), [Pro(34)]PYY (selective for Y(1)), and PYY-(3-36) (selective for Y(2)) to determine whether solution conformation plays a role in receptor subtype selectivity. The three peptides exhibited the expected specificities in displacing labeled PYY-(1-36) from cells transfected with Y(1) receptors (dissociation c...

BACKGROUND Improved delineation of vascular structures is a common indication for cardiovascular magnetic resonance (CMR) in children and requires high spatial resolution. Currently, pre-contrast 3D, respiratory navigated, T2-prepared, fat saturated imaging with a bSSFP readout (3D bSSFP) is commonly used; however, these images can be limited by blood pool inhomogeneity and exaggeration of meta...