The current study investigated the association between vitamin-D-receptor (VDR) genotypes with bone-mineral density (BMD) and its interaction with physical activity level (PAL). Individuals in a sample of 192 volunteers (67.84 +/- 5.23 years) underwent BMD evaluation and were genotyped for VDR ApaI, BsmI, FokI, and TaqI polymorphisms. Haplotypes were reconstructed through expectation-maximizati...

A finding of high BMD on routine DXA scanning is not infrequent and most commonly reflects degenerative disease. However, BMD increases may also arise secondary to a range of underlying disorders affecting the skeleton. Although low BMD increases fracture risk, the converse may not hold for high BMD, since elevated BMD may occur in conditions where fracture risk is increased, unaffected or redu...

Abstract Background and Aims Low bone mass is common in malnourished patients with chronic kidney disease (CKD) can lead to higher risk of fractures. Elderly CKD have the same factors for protein energy wasting, sarcopenia, osteoporosis. We attempted investigate an association between phase angle (PhA) mineral density (BMD) dialysis naïve stage 5 CKD, identify a statistical relationship PhA age...

Bone mineral density (BMD) is affected by lean body mass and body weight to various degrees in the course of aging. The attempt of this study is to determine the optimal time to begin prevention of osteoporosis. In this study, female hospital employees aged 20-59 years were divided into 2 age groups, 20-39 years and 40-59 years based on age at peak BMD, and the relations of total BMD, subtotal ...

BACKGROUND Lean mass is positively associated with bone mineral density (BMD). However, the relationship between adiposity and BMD is more controversial. In particular, it is unclear if the observational association between the two reflects a causal effect of fat mass on BMD. Previous Mendelian randomization (MR) studies using variants in the FTO and MC4R genes as genetic instruments for adipos...

Ethnic-specific normative data of bone mineral density (BMD) is essential for the accurate interpretation of BMD measurement. There have been previous reports of normative BMD data for Caucasian and Asian children including Japanese, Chinese, Korean and Indian. However, the normative BMD data for Southeast Asian including Thai children and adolescents are not currently available. The goals of o...

Abstract Small- and medium-sized enterprises (SEMs) are the important part of economic society whose innovation activities great significance for building innovative country. In order to investigate how technological (TI) business model design (BMD) affect performance SMEs, samples 268 SMEs in artificial intelligence industry hierarchical regression models used analysis. The results indicate th...

The risk of fractures is multifactorial and is related to the ability of bone to resist fracturing, which depends on its material and structural properties, and on the intensity, frequency and impact of trauma. Low BMD is a major determinant of bone strength and fracture risk. However, most patients with a fracture have no osteoporosis and BMD explains <50% of bone strength and fracture risk. B...

Results Females constituted 84% of the cohort with a median age at diagnosis of 13.1 years. The mean LS BMD zscores decreased with time. Initially, 9% of patients had a low BMD, this proportion increased to 19% by 3 years after diagnosis. Overall, the BMD category decreased in 35% of patients from 1 to 3rd DEXA study. LS BMD followed a general deteriorating trajectory of -0.25 z-score/year from...

Polymorphisms in the LRP5 gene have been associated with bone mineral density (BMD) in men and/or women. However, the functional basis for this association remains obscure. We hypothesized that LRP5 alleles could modulate Wnt signaling and the relationship between physical activity and BMD. This genetic association study was performed in the population-based Framingham Study Offspring Cohort, a...