In an attempt to establish a radioimmunoassay (RIA), imipramine and amitriptyline immunogens were prepared; desmethyl derivatives were converted into hemisuccinates, conjugated with bovine serum albumin and used for rabbit immunization. [3H]Amitriptyline (4.3 TBq/mmol) and [3H]imipramine (2.9 TBq/mmol) were prepared by catalytic dehalogenation or reductive alkylation. Dibenzazepines and dibenzc...

The objective of present study is to determine seasonal changes in biochemical content freshwater bivalve, Parreysia cylindrica relation heavy metal pollution Jayakwadi reservoir. Heavy concentrations were determined seasonally from surface water, soil sediment and soft body tissues cylindrica. highest during summer season than winter monsoon season. Protein, DNA, RNA Ascorbic acid estimated su...

the aim of this study is to determine of mercury levels in various internal organs of the fereydunkenar international wetland’s birds for the first time and to determine the influence of this metal on their health. this study has been done in the fereydunkenar international wetland where is the most important wetland habitat of the central areas of hyrcanian ecosystem. fereydunkenar internation...

Levels of biopterin derivatives in urine, serum, milk, cerebrospinal fluid, brain, and liver have been measured with the Crithidia fasciculata assay. Normal levels in serum and urine have been given and compared with those in a number of benign and malignant proliferative disorders, phenylketonuria, kidney disease, Parkinson's disease, schizophrenia, controlled epilepsy, rheumatoid arthritis, a...

Innate, non-specific, resistance mechanisms are important barriers to pathogens, particularly delaying virus multiplication at the onset of infections. These innate defense mechanisms include a series of mechanical barriers, pre-existing inhibitory molecules, and cellular responses with antimicrobial activity. The antiviral activities of these innate inhibitors reside in a variety of partly cha...

background: cadmium (cd) is an extremely toxic metal and environmental exposure to cd has been particularly problematic in the world. oral exposure to cd may result in adverse effects on a number of tissues, the immune system, and the cardiovascular system. compounds containing cd are also carcinogenic. the presence of cd in drinking water resources in the southeastern region of rafsanjan plain...

Exposure of conscious animals to environmental heat stress increases portal venous radical content. The nature of the observed heat stress-inducible radical molecules suggests that hyperthermia produces cellular hypoxic stress in liver and intestine. To investigate this hypothesis, conscious rats bearing in-dwelling portal venous and femoral artery catheters were exposed to normothermic or hype...

In recent years non-invasive medical diagnostic techniques have been used widely in medical investigations. Among the various imaging modalities available, Magnetic Resonance Imaging is very attractive as it produces multi-slice images where the contrast between various types of body tissues such as muscle, ligaments and fat is well defined. The aim of this paper is to describe the implementati...

Biomarkers are present in all parts of the body including body fluids and tissues. Most of the clinical laboratory examinations are done on body fluids such as blood and urine. Biomarkers can be detected on imaging studies or examination of body tissues. Even exhaled breath contains biomarkers. A wide range of technologies is utilized for detection of biomarkers and a number of assays are alrea...

1 Project Summary The goal of this research is to develop a general-purpose computational scheme for representing the geometry and physics of human-body soft-tissue structures and simulating their displacements and deformations in real-time when external forces are applied by surgical instruments. The ability to realistically model soft tissues on a computer has the potential to radically chang...