The major histocompatibility complex (MHC) is central to maintaining the immunologic vigor of individuals and populations. Classical MHC class II genes were targeted for partial sequencing in sea otters (Enhydra lutris) from populations in California, Washington, and Alaska. Sequences derived from sea otter peripheral blood leukocyte mRNAs were similar to those classified as DQA, DQB, DRA, and ...

Data quality assessments (DQA) are necessary to ensure valid research results. Despite the growing availability of tools relevance for DQA in R language, a systematic comparison their functionalities is missing. Therefore, we review packages related data (DQ) and assess scope against DQ framework observational health studies. Based on search, screened more than 140 Comprehensive Archive Network...

Za týmto názvom sa skrýva viacero skutočností: predovšetkým život a dielo profesora Jána Horeckého, ktorý iste nie je neznámy ani českej lingvistickej verejnosti; esej, ktorú J. Horecký predniesol na konferencii venovanej jeho osemdesiatinám a ktorá bola uverejnená v Jazykovednom časopise (2000, č. 1, s. 3 – 7; dostupný aj na http://www.juls.savba.sk/ediela/jc/); napokon je to aj názov celej vý...

Abstract We consider a model of bilayer lipid membrane with bola-lipids. The bola-lipid is modeled by linking tails of the hydrophobic chains in the opposite monolayers within bilayer as a first approximation. A number of thermodynamical characteristics are calculated analytically and compared with the ones of a regular membrane without chains linkage. Pronounced difference between lateral pres...

Southern hybridisation was used to define an apparent gene duplication event at the ovine DQA2 locus. Approximately 500 sheep from five different breeds were genotyped at their DQA1 and DQA2 loci. A subset of these were selected for further characterisation. Southern hybridisation of TaqI digested DNA revealed no DQA1 region in some sheep. It was also noted in these DQA1 null animals the DQA2 s...

background: myasthenia gravis is an autoimmune disorder of neuromuscular junction characterized by skeletal muscle weakness and fatigability. different genes may control the induction and clinical presentation of this disease. various hla alleles are reported as predisposing or protective genetic elements in myasthenia gravis. objective: the aim of this study was to investigate the probable ass...

Robotika preniká do rôznych foriem dennej aj mimoškolskej výučby na Slovensku už niekoľko niekoľko desaťročí. Je veľmi špecifickou oblasťou vzhľadom na jej interdisciplinárnosť, vhodnosť využitia v projektovej výučbe, vysoký motivačný faktor, technickú náročnosť a vysoké požiadavky na technické a odborné zabezpečenie. Jednou z vhodných foriem pre vytvorenie prostredia na efektívne, úspešné, zau...