Bourne (1944), describing the healing mechanism in tilt femoral defects, slated that initially they are filled by osteoid proliferation from the periosteum. Ma/.arow (I960) found that in the dog mandible the defect is tilled in from its cut surface and by bone trabeculae stemming chiefly from the periosteum. Mclchcr and Irving (1962) studied the healing mechanism in circumscribed defects in rat...

this study was perfomed on twenty five teeth which showed radiographic lesions( 6mm over 25 mm). the teeth were arranged in seven different groups and root canal therapy ( by warm gutta-percha technique) as surgical intervention were performed at various time intervals. in this investigation, histologic studies of the periapical tissues begin shortly after elimination of the root canal system w...

Bone formation in adults determines the basic mass of bone and hence it is crucial to understand the mechanisms of its regulation. As remodeling is proceeding, bone resorption is determined by the physical conditions. Especially in women, postmenopausal bone loss is characterized by rapid bone loss due to increase in bone resorption and relative negative balance between such bone resorption and...

Osteoporosis is a systemic skeletal disease and there is a close relationship between the sympathetic nervous system (SNS) and bone metabolism. Leptin has been shown to regulate bone formation and bone resorption via the SNS. However, the effect of SNS on leptin signaling has not been clearly understood. In the present study, we studied the effect of propranolol on ovariectomy-induced osteoporo...

We report a case of an osteonecrosis-like lesion of the knee that developed shortly after an arthroscopic medial meniscectomy. Clinical presentation, physical findings, and imaging of the knee including magnetic resonance imaging were similar to those of the cases that have been reported as osteonecrosis after meniscectomy. However, histologic analysis of the lesion revealed that there was no o...

The vast majority of the longitudinal growth of a typical mammalian long bone occurs at the ends of the bone in platelike structures termed growth plates. Both growth plates, one at the proximal end and the other at the distal end, are peripheral extensions of the primary center of ossification, a structure that arises in the midportion of the cartilaginous anlage of the bone-to-be during early...