AIMS To assess the feasibility of training nurse practitioners to perform bone marrow aspiration and trephine biopsy, and to compare the quality of these samples with those obtained by medical staff. METHODS A retrospective audit was undertaken of nurse practitioner and medical staff performance in bone marrow procedures in a busy haematology day unit. RESULTS Nurse practitioners fared favo...

Myelofibrosis (MF) is a rare disorder that classified as one of the myeloproliferative disorders. It BCR-ABL1- negative neoplasm characterized by abnormal proliferation hemopoietic stem cells within bone marrow, which leads to overproduction fibrous tissue. Our patient young girl 17 year old presented with lump in left upper abdomen, shortness breath & generalized swelling. The diagnosis wa...

Bone marrow biopsies ( 244) performed buffy coat. The greatest variance was seen with a Jamshidi needle were evaluated in the hypercellular or normocellular marin 53 children with leukemia or aplastic rows, as estimated by biopsy, in which anemia. Adequate specimens were ob39% were misinterpreted as moderately tamed in 85%. Results of cellularity estior severely hypocellular by aspirate. Volmat...

Bone marrow aspirates and biopsy specimens were taken at diagnosis from 51 patients with acute myeloid leukaemia (AML). The diagnosis was based on morphological and cytochemical analyses, and the leukaemias were classified by FAB criteria. A considerable difference was observed between the results of bone marrow aspirates and the findings of plastic-embedded bone marrow biopsy specimens, partic...

We compared the sensitivity of bone marrow biopsy to blood flow cytometry in detecting minimal residual disease (MRD) in 29 patients with chronic lymphocytic leukemia (CLL) in clinical remission after treatment. These results demonstrate that flow cytometry is more sensitive than bone marrow biopsy in detecting MRD and in predicting relapse in CLL.

Objective: The bone marrow is the primary site for blood cell formation, responsible production and export of red cells, platelets, granulocytes. Pancytopenia a condition characterized by reduction in all three types cellular components peripheral blood, leading to symptoms failure. management prognosis pancytopenia depend on identifying underlying pathology.
 Methods: pathophysiology invo...