INTRODUCTION Stress fracture of the clavicle is a rare entity. It can manifest itself with an atypical shoulder pain. The clavicle is vulnerable to pathological fractures from several causes such as neoplasm, infection and rarely metabolic bone disease. CASE PRESENTATION We report a case of a bone insufficiency fracture of the clavicle, in a 67-year-old Moroccan woman patient with several ris...

The excess release of mediators can cause clinical features such as pruritus, flushing, nausea, vomiting, diarrhoea, abdominal pain, vascular instability and anaphylaxis. Also, complications may arise when mast cells accumulate in the skin, gastrointestinal tract, bone marrow, liver, spleen, and lymph nodes. [2] The clinical features of systemic mastocytosis are caused by accumulation of clonal...

Ossifying fibroma is a slow growing benign neoplasm usually Involving bones of the skull and face, mainly mandible maxilla. The tumor composed bone that develops within fibrous connective tissue, sometimes with cementum-like calcifications. Clinical presentation asymptomatic, rarely presented facial asymmetry, swelling, pain, bowing long bones. Radiological investigations are computed tomograph...

BACKGROUND To estimate the costs (paid amounts) of palliative radiation episodes of care (REOCs) to the bone for patients with bone metastases secondary to breast or prostate cancer. METHODS Claims-linked medical records from patients at 98 cancer treatment centers in 16 US states were analyzed. Inclusion criteria included a primary neoplasm of breast or prostate cancer with a secondary neopl...

changes here described from the appearance of secondary neoplasm, particularly neuroblastoma, may be difficult, and the diagnosis may only become clear with evolution of more typical radiological appearances. Eversole, Holman, and Robinson in 1957 described focal resorption of cortical bone as an early microscopical feature in the evolution of infantile cortical hyperostosis. The relative vascu...

Ewing's sarcoma (ES) is the second most common malignant bone tumor in children and young adults. ES also occurs as a primary soft tissue neoplasm without involvement of bone. We report the second case of extraosseous (EO) ES emerging from the omentum and a review of the relevant literature. EO ES should be included in the differential diagnosis of soft tissue neoplasms in the abdomen.

Primary bone tumors are a relatively rare neoplasm, however, they are a source of significant patient morbidity. Many, in fact, possess the ability to degenerate into malignant metastatic cancers. Early detection, from patient history and radiographic analysis, is of the utmost importance in identifying potential cancerous bone lesions. Using a systematic approach with radiographic analysis, it...

Desmoplastic small round cell tumor is an extremely rare and highly aggressive neoplasm. It usually arises as a single mass or multiple masses in the abdominal cavity, characterized by diffuse peritoneal implants, involvement of regional lymph nodes, and liver and lung metastases. However, bone marrow metastasis has rarely been reported in the literature. We present a case of clinically symptom...

Heterotopic bone formation is a very rare event in the gastrointestinal tract including in the appendix. Here we report three cases of heterotopic ossification in appendiceal mucinous neoplasms, one occurring in an appendiceal mucinous cystadenoma, another in a low-grade appendiceal mucinous neoplasm, and the third occurring in an appendiceal mucinous adenocarcinoma. The clinicopathologic chara...

Chronic myelomonocytic leukemia (CMML) is a myelodysplastic/myeloproliferative neoplasm characterized by the infiltration of blood and bone marrow immature monocytes, in which extra-hematopoietic localization uncommon. We report case 69-year-old-man with highly likely ectopic brain CMML involvement MRI. Without possibility cerebral biopsy negative infectious disease assessment, high-dose cytara...