The aim of the present study was to assess the efficacy of a ready-to-use injectable bone substitute on the prevention of alveolar ridge resorption after tooth extraction. Maxillary and mandibular premolars were extracted from 3 Beagle dogs with preservation of alveolar bone. Thereafter, distal sockets were filled with an injectable bone substitute (IBS), obtained by combining a polymer solutio...

A case of a traumatic periprosthetic acetabular fracture in an elderly patient, which was treated by one-stage hip exchange with implantation of an antiprotrusio cage and reconstruction of the acetabular bone loss with an injectable calcium sulphate/hydroxyapatite bone graft substitute, is reported. The paste-like bone graft substitute was injected through the holes of the antiprotrusio cage. A...

SUPERCRITICAL CARBON DIOXIDE-PROCESSED RESORBABLE POLYMERNANOCOMPOSITES FOR BONE GRAFT SUBSTITUTE APPLICATIONSbyKEVIN C. BAKERAugust 2011Advisor: Rangaramanujam M. Kannan, Ph.D.Major: Biomedical EngineeringDegree: Doctor of PhilosophyNumerous clinical situations necessitate the use of bone graft materials to enhance boneformation. While autologous and all...

INTRODUCTION: Composites of purified collagen and calcium phosphate salts have been widely used to produce osteoconductive scaffolds for fracture healing and spinal fusion. The effects of different calcium phosphate additives in a collagen scaffold was previously investigated in a rat model of ectopic bone formation induced by a mixture of bovine bone derived growth factors. It was found that o...

BACKGROUND Tibial head depression fractures demand a high level of fracture stabilization to prevent a secondary loss of reduction after surgery. Elderly individuals are at an increased risk of developing these fractures, and biomechanical investigations of the fractures are rare. Therefore, the aim of this study was to systematically analyze different types of osteosyntheses in combination wit...

OBJECTIVES Deep bone and joint infections (DBJI) are directly intertwined with health, demographic change towards an elderly population, and wellbeing.The elderly human population is more prone to acquire infections, and the consequences such as pain, reduced quality of life, morbidity, absence from work and premature retirement due to disability place significant burdens on already strained he...

Although the use of calcium sulfate has been used as a bone graft substitute in the treatment of fractures for more than a century, few studies investigate the use of recently developed injectable calcium sulfate-based bone graft substitute with high compressive strength after curing in situ. In this study, we evaluated preliminary results of a high compressive strength calcium sulfate-based bo...