Over the past decade, we have witnessed exponential growth in the density (petabyte-level) and breadth (across geo-distributed datacenters) of data distribution. It becomes increasingly challenging but imperative to minimize the response times of data analytic queries over multiple geo-distributed datacenters. However, existing scheduling-based solutions have largely been motivated by pre-estab...

During designing a business process model, to predict its performance is very important. The performance of business operational process is heavily influenced by its bottlenecks. In order to improve the performance, finding the bottlenecks is critical. This paper proposes a theoretical analysis method for bottleneck detection. An abstract computational model is designed to capture the main elem...

Identifying the location of performance bottlenecks is a non‐trivial challenge when scaling n‐tier applications in computing clouds. Specifically, we observed that an n‐tier application may experience significant performance loss when bottlenecks alternate rapidly between component servers. Such rapidly alternating bottlenecks arise naturally and often from resource dependencies in an n‐tier sy...

Lijie Heng 9032366867 Contributions of the Paper This paper investigates potential non-access bottlenecks which may arise after fixing the bottlenecks at the edges of the network by updating the access links in the future. The first contribution of this paper is to propose a good method for measuring the non-access Internet bottleneck links by choosing representative sources and destinations. B...

Various strategies have been developed to exploit plants as bioreactors for the production of pharmaceutical antibodies, to engineer antibody-mediated pathogen resistance or to alter the plant phenotype by immunomodulation. Recent research developments focus on the fine-tuning of expression systems and the detailed characterisation of recombinant products, including the implications of plant-sp...

The characteristics of natural populations result from different stochastic and deterministic processes that include reproduction with error, selection, and genetic drift. In particular, population fluctuations constitute a stochastic process that may play a very relevant role in shaping the structure of populations. For example, it is expected that small asexual populations will accumulate mut...

Recently many overlay multicast systems have been proposed to overcome limited availability of IP multicast. Because they perform multicast forwarding without support from routers, data may be delivered multiple times over the same physical link, causing a bottleneck. This problem is more serious for applications demanding high bandwidth such as multimedia distribution. Although such bottleneck...

We present MONITORMETHOD, a tool which helps Java programmers gain insight in the behavior of their applications. MONITORMETHOD instruments the Java application and relates hardware performance monitors (HPMs) to the methods in the Java application’s source code. We present a detailed case study showing that linking microprocessor-level performance characteristics to the source code is helpful ...

To model deviations from selectively neutral genetic variation caused by different forms of selection, it is necessary to first understand patterns of neutral variation. Best understood is neutral genetic variation at a single locus. But, as is well known, additional insights can be gained by investigating multiple loci. The resulting patterns reflect the degree of association (linkage) between...