1. Following heat denaturation after an hour at boiling temperature bovine testicular hyaluronidase has been shown to undergo spontaneous reactivation. 2. This reactivation is a function of the temperature at which the enzyme solution is maintained. 3. Secondary inactivation was observed to follow a reactivation of the enzyme at all concentrations observed. 4. There is a relationship between hy...

OBJECTIVE To study whether acute lymphoblastic leukemia (ALL) cells survive in a human testicular cell culture system. DESIGN Experimental laboratory study. SETTING Reproductive biology laboratory, academic medical center. PATIENT(S) Acute lymphoblastic leukemia cells from three patients and testicular cells from three other patients. INTERVENTION(S) Acute lymphoblastic leukemia cells w...

the adrenal gland of notopterus notopterus (pallas) consisted of interrenal and chromaffin cells, distributed around the main branches of posterior cardinal vein in most anterior part of the pronephric kidney. seasonal histological characteristics of the interrenal and chromaffin cells in relation to testicular activity of n. notopterus were studied by adopting different staining techniques. th...

The field of spermatogonial stem cell (SSC) technologies provides tools for genetic improvement of cattle herds and multiple opportunities for research. Spermatogonial stems cells belong to the male germ line and as such have high developmental potential, which offers many possibilities for transfer of relevant genetic traits across herds in a timely manner. Type A spermatogonia include a very ...

Hormone-sensitive lipase (HSL, Lipe, E.C.3.1.1.3) is a multifunctional fatty acyl esterase that is essential for male fertility and spermatogenesis and that also plays important roles in the function of adipocytes, pancreatic beta-cells, and adrenal cortical cells. Gene-targeted HSL-deficient (HSL-/-) male mice are infertile, have a 2-fold reduction in testicular mass, a 2-fold elevation of the...

The goal of this study was to establish an optimal in vitro growth assay system for human urological tumor explants. Bovine corneal endotelial cell extracellular matrix (ECM) coated dishes were evaluated as a growth substrate for tumor cultures. Growth success for different urological carcinomas (prostatic, bladder, kidney, and testicular) was compared after seeding fresh surgical explants onto...

The goal of this study was to establish an optimal in vitro growth assay system for human urologica! tumor expiants. Bovine corneal endotelial cell extracellular matrix (ECM) coated dishes were evaluated as a growth substrate for tumor cultures. Growth success for different urologica! carcinomas (prostatic, bladder, kidney, and testicular) was compared after seeding fresh surgical expiants onto...

testicular cancer is one of the commonest cancers in men of working age, and is increasing in incidence in europe and north america. one suggested mechanism of causation is that there is impaired differentiation of germ cells in the pre- or perinatal period, followed by malignant transformation in later life, possibly by a hormonal mechanism. endocrine disrupting chemicals (edcs) have been a ma...

Objective- The purpose of this study was to evaluate the protective impacts of Plantago. major (P. major) against the adverse effects resulted from testicular ischemia/reperfusion (I/R) on kidney and liver.Design- Experimental study.Animals- Twenty-four male rats.Procedures- The testicular I/R was induced by f...