نتایج جستجو برای: brain radiotherapy
تعداد نتایج: 530728 فیلتر نتایج به سال:
Although meningioma is the most common primary brain tumour no strict consensus exists on the exact role of radiotherapy due to the lack of controlled phase-III studies. In completely resected grade-I tumours, radiotherapy is usually deferred until possible recurrence. For grade-II–III tumours, the issue is more controversial and radiotherapy is occasionally applied already in the primary setti...
BACKGROUND We determined the impact of genetic alterations in EGFR, ALK, or KRAS on survival after radiotherapy for brain metastases in non-small cell lung cancer (NSCLC). METHODS Of 172 genotyped NSCLC patients treated with radiotherapy for brain metastases in 2005-2012, 54 had cancers with EGFR mutations, 12 had ALK rearrangements, 38 had KRAS mutations, and 68 were wild-type (WT). Overall ...
Objective—To assess the eVect of postoperative radiotherapy on brain glucose metabolism (CMRGlu) of operated patients with low grade astrocytomas. Methods—PET and F-fluorodeoxyglucose was used to measure absolute CMRGlu in patients with fibrillary astrocytoma (WHO II) of the frontal lobe, who did (n=7) or did not (n=12) receive radiotherapy subsequent to first debulking tumour resection. In add...
Conventional radiotherapy in the form of whole brain radiation treatment has been a longstanding treatment for brain metastases, and it continues to provide effective palliation as monotherapy and in combination with local and systemic treatments. Advances in systemic therapy have improved survival with metastatic disease, and in those patients with better prognostic factors, more aggressive lo...
BACKGROUND In this report we present the results of the retrospective (survival and classification) analyses of possible prognostic factors prolonging survival in epithelial ovarian cancer brain metastases patients after stereotactic radiotherapy. We focus on a wide range of available predictors to establish survival in patients with a good health status and no more than three lesions. METHOD...
We would like to thank David Ratel, Boudewijn van der Sanden, and Didier Wion for their comments, and to further develop their interesting hypothesis. Compelling evidence demonstrates that radiotherapy, as well as surgery, improves glioblastoma survival. However, in recent years certain reports have highlighted the contradictory effect of radiotherapy, which also stimulates the expression of in...
Brain metastases from gynecological cancers were retrospectively investigated in 18 patients who were treated between 1985 and 2006. Six patients received surgical resection followed by radiotherapy, and 12 patients received only radiotherapy. The median survival for all patients was 4.1 months (range 0.7-48.2 months), and the actuarial survival rates were 11% at both 12 months and 24 months. U...
Reirradiation is a challenging field in the treatment of recurrent brain metastases. Because of the elevated risk of radiation toxicity due to previous irradiation, only a limited dose is prescribed. To enhance radiosensitivity, in the present analysis six patients received hypofractionated stereotactic radiotherapy (hSRT) with daily oral administration of the hypoxic sensitizer AK-2123 (sanazo...
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