PURPOSE Our practice policy has been to provide intraoperative radiotherapy (IORT) at resection to patients with head-and-neck malignancies considered to be at high risk of recurrence. The purpose of the present study was to review our experience with the use of IORT for primary or recurrent cancer of the parotid gland. METHODS AND MATERIALS Between 1982 and 2007, 96 patients were treated wit...

482. 9. Haviland JS, A’Hern R, Bentzen SM, et al. Radiotherapy for breastcancer: The TARGIT-A trial. Lancet 2014;383:1716-1717. 10. The TARGIT-A trial protocol. http://www.nets.nihr.ac.uk/projects/hta/076049 and http://www.targit.org.uk. Accessed May 11, 2015.11. Hughes KS, Schnaper LA, Bellon JR, et al. Lumpectomy plustamoxifen with or without irradiation in women age 70 years ...

AIM The investigation of the irradiation time calculation accuracy of the GGPB algorithm used for IORT. BACKGROUND Conventionally, breast conserving therapy consists of breast conserving surgery followed by postoperative whole breast irradiation and boost. The use of intraoperative radiotherapy (IORT) enables the boost to be delivered already during the surgery. In this case, the treatment do...

Radiotherapy (or radiation therapy) uses ionizing to selectively kill cancer cells, especially for solid tumours. Like surgery, it is meant be a ‘local’ treatment, although its beneficial systemic effects are being discovered. It most commonly used in addition surgery (adjuvant, e.g. breast), but role the neoadjuvant setting combination with chemotherapy some cancers (e.g. rectum) also establis...

  Background: Intra-operative radiation therapy (IORT) is the transfer of a single large radiation dose to the tumor bed during surgery with the final goal of improving regional tumor control. This study aimed to investigate the safety, effectiveness and economic evaluation of intra-operative radiation therapy.   Methods : The scientific literature was searched in the main biomedical databases ...

Purpose: To review a single-institutional experience with the use of intraoperative radiation therapy (IORT) for recurrent head-and-neck cancer. Methods and Materials: Between 1991 and 2004, 137 patients were treated with gross total resection and IORT for recurrence or persistence of locoregional cancer of the head and neck. One hundred and thirteen patients (83%) had previously received exter...

PURPOSE To analyze the outcomes of therapy and identify prognostic factors for patients treated with surgery followed by intraoperative radiotherapy (IORT) for gynecologic malignancies at a single institution. METHODS AND MATERIALS We performed a retrospective review of 36 consecutive patients treated with IORT to 44 sites with mean follow-up of 50 months. The primary site was the cervix in 4...

BACKGROUND To present the technique and dose distribution of intraoperative radiotherapy (IORT) for prostate cancer. PATIENTS AND METHODS Pelvic lymphadenectomy, prostate IORT and radical retropubic prostatectomy was performed in 11 prostate cancer patients. Prostate thickness and rectum depth were measured with intraoperative ultrasound. IORT was delivered by a mobile linear accelerator in t...

Intraoperative radiation therapy (IORT) has been customarily performed either in a shielded operating suite located in the operating room (OR) or in a shielded treatment room located within the Department of Radiation Oncology. In both cases, this cancer treatment modality uses stationary linear accelerators. With the development of new technology, mobile linear accelerators have recently becom...