breast cancer is the most common cancer in women worldwide. breast cancer in one third of all patients will go on to metastasis, which is the main cause of mortality in cancer cases. tumor cells detach from primary tumor and enter into the circulation as circulating tumor cells (ctcs) which can form metastatic lesions. in this study, the expression of ck-19 gene in blood samples of metastatic b...

Although often localized at diagnosis, nasopharyngeal carcinoma (NPC) has an established potential for distant metastasis. Breast metastasis from NPC is an uncommon presentation. In the present case study, the fifth reported case of breast metastasis from NPC is presented and the use of Epstein-Barr virus testing is demonstrated for the confirmation of this diagnosis. A 49-year-old female was d...

Background. Primary ovarian carcinoma with metastasis to the breast is rare, with only 39 cases reported in the current literature. Ovarian metastasis to the breast presenting as inflammatory breast carcinoma is even more infrequent, with only 6 cases reported.Case. We present a patient who developed metastatic inflammatory cancer of the breast from a stage IIIC papillary serous ovarian adenoca...

Metastasis is the most common cause of mortality in breast cancer patients worldwide. To identify improved mouse models for breast cancer growth and spontaneous metastasis, we examined growth and metastasis of both estrogen receptor positive (T47D) and negative (MDA-MB-231, SUM1315, and CN34BrM) human breast cancer cells in nude and NSG mice. Both primary tumor growth and spontaneous metastases...

Purpose Bone is one of the most common sites of breast cancer metastasis, and population-based studies of patients with bone metastasis in initial metastatic breast cancer (MBC) are lacking. Materials and methods From 2010 to 2013, 245,707 breast cancer patients and 8901 patients diagnosed with initial bone metastasis were identified by Surveillance, Epidemiology, and End Results database of ...

Two female patients were diagnosed with primary small cell carcinoma of the breast that was estrogen receptor, progesterone and Her-2 Neu negative. Diagnosis made by ultrasound-guided core needle biopsy. They both underwent neoadjuvant chemotherapy. The first patient had negative sentinel lymph node biopsy postoperative whole radiation. She has remained disease-free. second preoperative radiati...

To examine the effect of TBMS1on breast cancer metastasis, and investigate the potential mechanism by which Tubeimoside- 1 (TBMS1) inhibits the CXCR4 expression in breast cancer cells. The expression of CXCR4 in breast cancer cell lines was determined by immunoblotting and real-time PCR. The effect of TBMS1 on NF-κB binding activity was evaluated by EMSA assay and ChIP analysis. Cell proliferat...

Invasive micropapillary variant of mucinous carcinoma breast is an under-recognized category which shares features both pure and invasive carcinoma. Due to its greater propensity for nodal metastasis angioinvasion, the prognosis in this subtype worser than breast. Here we report a case 43-year-old female.

background: determination of the impact of angiogenesis on tumor development and progression is essential. this study aimed to determine the serum levels of vascular endothelial growth factor (vegf) and interleukin 6 (il-6) in breast carcinoma, and to correlate them with tumor size, lymph node involvement, and cancer stage. methods: under aseptic precautions 5 ml of venous blood was collected f...