A 51-year-old female patient underwent 18F-FDG PET/CT searching for the cause of a fever of unknown origin. Before 18F-FDG injection, the patient had fasted for at least 6 h; at the time of the radiopharmaceutical injection the glucose blood levels corresponded to 96 mg/dL. Images were acquired 1 h after i.v. injection of 280 MBq of 18F-FDG. 18F-FDG PET/CT showed an area of increased radiopharm...

BACKGROUND Worldwide, over half a million women died of breast cancer in 2011 alone. Mammography screening is associated with a reduction of 20 to 35% in breast cancer mortality. The aim of this study was to determine the awareness and practice of mammography screening and predictors of its uptake in Malaysian women attending a primary care clinic. MATERIALS AND METHODS A cross-sectional stud...

OBJECTIVE To evaluate the clinical value of 16α-[18F]fluoroestradiol (18F-FES) PET/CT in assisting the individualized treatment decisions of breast cancer patients. METHODS Thirty-three breast cancer patients, who underwent both 18F-FES and 18F-FDG PET/CT from July 2010 to March 2013 in our center, were enrolled in this preliminary study. All the patients used 18F-FES PET/CT as a diagnostic t...

The purpose of this study was to investigate the differential expression and function of organic anion-transporting polypeptides (OATPs) in breast epithelial and breast cancer cells. Estrone-3-sulfate (E3S), a substrate for 7 of 11 OATPs, is a predominant source of tumor estrogen in postmenopausal, hormone-dependent patients with breast cancer. Overexpression of certain OATPs (e.g., OATP1A2) re...

BACKGROUND Breast cancer affects up to one in 12 women in the UK. Breast awareness, which is advocated in place of routine breast examination, involves women becoming more familiar with their bodies. CONCLUSION Nurses have a vital role to play in encouraging women to become more breast aware. Their health promotion activities in this area can have an important impact on the uptake of breast s...

Conventional chemotherapeutic treatments for breast cancer produce high systemic concentrations while local concentrations in the diseased tissue are relatively low. In contrast, targeted therapeutics provide the promise of low systemic dosage, and therefore, modest or no side effects, while producing high local concentrations at the tumor. Fluorescent, 20nm diameter, calcium phosphosilicate na...

OBJECTIVES To examine the effectiveness and cost-effectiveness of two interventions based in primary care aimed at increasing uptake of breast screening. SETTING 24 General practices with low uptake in the second round of screening (below 60%) in north west London and the West Midlands, UK. Participants were all women registered with these practices and eligible for screening in the third rou...

BACKGROUND Ecological or survey based methods to investigate screening uptake rates are fraught with many limitations which can be circumvented by record linkage between Census and health services datasets using variations in breast screening attendance as an exemplar. The aim of this current study is to identify the demographic, socio-economic factors associated with uptake of breast screening...

osteopoikilosis is a rare benign osteosclerotic bone disorder that may be misdiagnosed as skeletal metastases. here we describe a case of coincidental breast cancer and osteopoikilosis mimicking skeletal metastases. a 41-year-old woman underwent right modified radical mastectomy in april 2007. twenty-eight months after initial treatment, the patient complained of bilateral knee and foot pain. p...