نتایج جستجو برای: brucella abortus s19
تعداد نتایج: 7194 فیلتر نتایج به سال:
Introduction and objective: Outer membrane proteins (OMPs) of Brucella are considered as immunogenic structures which can be used to design and develop a subunit vaccine for human brucellosis. Brucella abortus S99 OMPs promote the synthesis of high levels of specific anti-Brucella IgG molecules in rabbits when administrated with lipopolysaccharide (LPS). The objective of this study is evaluatio...
OBJECTIVES Brucellosis is a major zoonotic disease that poses a significant public health threat worldwide. The classical bacteriological detection process used to identify Brucella spp. is difficult and time-consuming. This study aimed to develop a novel molecular assay for detecting brucellosis. METHODS All complete sequences of chromosome 1 with 2.1-Mbp lengths were compared among all avai...
Brucella abortus is generally known to cause brucellosis in cattle and buffalo. Here, we report the draft genome sequence of Brucella abortus SKN 13, isolated from aborted cattle placenta in the area of Gujarat, India, providing precious resources for comparative genomic analyses of Brucella field strains.
Knowing the inherent stimulatory properties of the lipid moiety of bacterial lipoproteins, we first hypothesized that Brucella abortus outer membrane protein (Omp)16 lipoprotein would be able to elicit a protective immune response without the need of external adjuvants. In this study, we demonstrate that Omp16 administered by the i.p. route confers significant protection against B. abortus infe...
Brucella abortus proteins from virulent S2308 expressed from a pBluescript II SK- genomic library stimulated peripheral blood mononuclear (PBM) cell proliferation from cattle vaccinated with B. abortus S19. The method described here permits a rapid and directed approach to isolate genes encoding antigens of B. abortus that interact with lymphocytes primed to the living bacterium. The supernatan...
background: the immunogenic brucella abortus ribosomal protein l7/l12 is a promising candidate antigen for the development of subunit vaccines against brucellosis. objective: this study was aimed to evaluate the protection of recombinant human serum albumin (has)-l7/l12 fusion protein in balb/c mice. methods: the amplified l7/l12 gene was cloned in pyhsa5 vector, pyhsa5-l7/l12 construct was tra...
Genomic Detection of Brucella Abortus in Milk obtained from Farms Lorestan Province using PCR Method
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