INTRODUCTION In the past 10 years, bullous pemphigoid has been associated with other comorbidities and neurologic and psychiatric conditions in particular. Case series, small case-control studies, and large population-based studies in different Asian populations, mainland Europe, and the United Kingdom have confirmed this association. However, no data are available for the Spanish population. ...

BACKGROUND Acute myringitis is an inflammation of the tympanic membrane that occurs alone or in association with external otitis or otitis media. The two clinical entities, based on physical examination, are bullous myringitis and hemorrhagic myringitis. OBJECTIVES To investigate the association of concomitant middle ear disease with acute myringitis and to analyze the bacteriologic findings ...

Bullous systemic lupus erythematosus has rarely been described in pediatric lupus population and the real prevalence of childhood-onset bullous systemic lupus erythematosus has not been reported. From January 1983 to November 2013, 303 childhood-onset SLE (c-SLE) patients were followed at the Pediatric Rheumatology Unit of the Childreńs Institute of Hospital das Clínicas da Faculdade de Medicin...

BACKGROUND The bullous variant of Darier's disease (DD) is a rare type characterized by histological and clinical overlap with Hailey-Hailey disease (HDD). CASE REPORTS The following case report describes two cases of familial DD; a 51-year-old woman who presented with erythematous plaques, covered by small blisters in axillary and inguinal areas, and the first patient's daughter, who present...

RESUMEN
 El Penfigoide ampollar es una enfermedad de tipo autoinmune que se origina por la producción autoanticuerpos contra diferentes componentes membrana basal. penfigoide vincula con padecimientos crónicos como diabetes mellitus, neoplasias, trastornos psiquiátricos o neurodegenerativos el accidente cerebrovascular, isquemia cerebral transitoria, Parkinson y Alzheimer entre otras.&#x0D...

Linear IgA disease (LAD) is a chronic, acquired, autoimmune bullous disease. Generalized bullous eruptions is not unusual in the intensive care unit. The cause can be idiopathic, autoimmune, or drug induced but prompt recognition is crucial to their management. The autoimmune blistering skin diseases are a heterogeneous group of diseases associated with autoantibodies that are directed against ...

Pemphigus vulgaris (PV) is an autoimmune disease characterized by blistering and erosions on skin and mucous membranes due to acantholysis. It is caused by autoantibodies against desmosomal caderins desmoglein 3 (Dsg 3) which are calcium dependent cell adhesion molecules. The measurement of Dsg 3-ELISA had been shown to be a sensitive and specific test for the diagnosis of PV in addition to the...

Bullous pemphigoid is the most common autoimmune blistering disease in industrialized countries and particularly affects elderly. In this patient population, comorbid diseases are frequent may complicate management treatment of bullous pemphigoid. A better understanding why distinct more patients lead to new pathophysiological insights - as a consequence result care. The association with neurol...

OBJECTIVES To evaluate treatment with methotrexate in patients with bullous pemphigoid and to elucidate the reduced adverse effects compared with standard treatment with prednisone. DESIGN Retrospective study (January 1, 1999-December 31, 2003). SETTING The Department of Dermatology and Venerology, Karolinska University Hospital. PATIENTS A total of 138 consecutive patients with bullous p...