Analogues of luteinising hormone-releasing hormone (LHRH) are very much in fashion. Their design is clever and they offer an effective medical alternative to surgical castra-tion in the treatment of breast and prostatic cancer. In breast cancer their use in metastatic disease is increasing steadily, and current enthusiasm is such that multicentre adjuvant therapy trials in early disease are alr...

The therapeutic options for the treatment of androgen-independent prostatic cancers are rather limited; this is mainly because our understanding of the local mechanisms involved in the control of androgen-independent proliferation of the tumor is still very poor. The present experiments have been performed to verify whether luteinizing hormone-releasing hormone (LHRH) agonists may possess a dir...

This study was designed to determine the effects of GnRH administration alone at time artificial insemination (AI) or in combination with hCG 5 days after injection on conception rates postpartum dairy cows. Cows estrus, without any reproductive health problem, between 70-120 were randomly assigned 3 equal groups. Buserelin acetate (10 µg), administered AI Group I (n=40). II (n=40) first μg) an...