Are There Asymmetries in the Effects of Training on the Conditional Male Wage Distribution? We use a quantile regression framework to investigate the degree to which work-related training affects the location, scale and shape of the conditional wage distribution. Human capital theory suggests that the percentage returns to training investments will be the same across the conditional wage distri...

The linker molecule LAT is a critical substrate of the tyrosine kinases activated upon TCR engagement. Phosphorylated LAT binds Grb2, PLC-gamma1, and other signaling molecules. We demonstrate that human LAT is palmitoylated and that palmitoylated LAT predominantly localizes into glycolipid-enriched microdomains (GEMs). Although the LAT transmembrane domain is sufficient for membrane localizatio...

We have measured the bile acids in human serum as methyl ester-trimethylsilyl ethers by gas chromatography-mass spectrometry (GC-MS) using an electron ionization procedure. The overall method was validated and the detection limit (0.4 mumol/l), linearity (2-30 mumol/l), intra-day and inter-day precision, accuracy and recovery (96.2% for nor-23-deoxycholic acid as internal standard) were measure...

Toxoplasma gondii can infect nearly all warm-blooded animals. We report an acute fatal T. gondii infection in the endangered giant panda (Ailuropoda melanoleuca) in a zoo in China, characterized by acute gastroenteritis and respiratory symptoms. T. gondii infection was confirmed by immunological and molecular methods. Multilocus nested PCR-RFLP revealed clonal type I at the SAG1 and c29-2 loci,...

Optical and H NMR techniques have been applied to the study of a few metal complexes (Co, Fe, and Yb) of the antitumor antibiotic streptonigrin (SN) produced by Streptomyces flocculus to elucidate the structure of the complexes. The hyperfine-shifted H NMR signals of these paramagnetic complexes were fully assigned by means of relaxation and two-dimensional NMR techniques. These studies reveale...

A family of C29 4,4-dimethylsterol intermediates in the cholesterol biosynthetic pathway from lanosterol has been found to induce oocytes to resume meiosis.[248] One of these sterols, 4,4-dimethyl-5α-cholest-8,14,24-triene-3β-ol, was extracted from human follicular fluid and named follicular fluid meiosis–activating substance (FF-MAS). A related compound, 4,4-dimethyl-5α-cholest-8,24-diene-3β-o...

Toxoplasma gondii atypical type II genotype was diagnosed in a pet peach-faced lovebird (Agapornis roseicollis) based on histopathology, immunohistochemistry, and multilocus DNA typing. The bird presented with severe neurological signs, and hematology was suggestive of chronic granulomatous disease. Gross post-mortem examination revealed cerebral hemorrhage, splenomegaly, hepatitis, and thicken...

Until recently, Toxoplasma gondii was considered to be clonal with little genetic variability. In this paper we summarize recent genotyping data from chickens in Brazil, and pigs, lambs and white-tailed deer in the USA, to demonstrate the high genetic diversity and geographical distribution of T. gondii. A total of 149 T. gondii isolates from 13 geographical areas of Brazil and 182 T. gondii is...

This study systematically analyzes the dark shale samples of Silurian Qusaiba Formation from Tayma Quadrangle outcrop section in northwest Saudi Arabia, and assesses source nature its organic matter main sedimentary environmental conditions during accumulation matter. The are characterized by total carbon (TOC) sulfur contents with values range 0.87–1.76 wt. % 0.59–4.64 %, respectively, indicat...