8 Other Available Therapies ................................................. 23 8.1 Danazol .................................................................................. 23 8.2 Cabergoline ............................................................................ 24 8.3 Gestrinone .............................................................................. 24 8.4 Oral Contraceptives ....

The use of octreotide-LAR and cabergoline therapy has shown great promise in adults with acromegaly; however, the experience in pediatric patients has rarely been reported. We described a clinical course of a 15-year-old boy of McCune-Albright syndrome (MAS) with pituitary gigantism. At the age of 8 years, a growth hormone (GH) and prolactin (PRL) producing pituitary adenoma was diagnosed at ou...

OBJECTIVE Dopamine agonists (DA) are the treatment of choice in patients with macroprolactinomas. Brain and optic chiasm herniation are unusual complications following treatment with DA. REPORT We present a case of a giant prolactinoma complicated by visual deterioration following cabergoline treatment. A 42-year-old man was admitted with seizures, right visual loss and visual defect in the u...

PURPOSE To report a case of bilateral acute angle-closure glaucoma after oral administration of cabergoline for the treatment of galactorrhea. METHODS A diagnosis of secondary drug-induced angle-closure glaucoma was made in a patient with elevated intraocular pressure (IOP) and myopic refractive shift, which was confirmed by ultrasound biomicroscopy (UBM) of the ciliary body and anterior segm...

BACKGROUND Whether the withdrawal of treatment in patients with nontumoral hyperprolactinemia, microprolactinomas, or macroprolactinomas is safe and effective has been unclear. We performed an observational, prospective study of cabergoline (a dopamine-receptor agonist) withdrawal in such patients. METHODS The study population included 200 patients--25 patients with nontumoral hyperprolactine...

To cite: Nanba K, Usui T, Nakakuki T, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013009986 DESCRIPTION A 28-year-old man diagnosed with multiple endocrine neoplasia type 1 (MEN1) was referred to us for medical treatment of macroprolactinoma. His serum prolactin level was 8071 ng/mL in diluted sample and brain MRI showed an invasive lobulated giant pit...

BACKGROUND 30% of patients with polycystic ovary syndrome (PCOS) show mild, transient hyperprolactinemia. It is suggested that a reduction of the dopamine inhibitory effect might raise both prolactin and luteinizing hormone. OBJECTIVE To investigate the adjuvant cabergoline therapy effects on menstrual irregularity and androgen system in PCOS women with hyperprolactinemia. MATERIALS AND MET...

We report an unusual case of subarachnoid hemorrhage caused by intraoperative rupture of an intracavernous carotid artery aneurysm coexisting with a prolactinoma. A 58-year-old man presenting with diplopia was found to have a left intracavernous carotid artery aneurysm encased by a suprasellar tumor on magnetic resonance imaging. His serum prolactin level was 5036 ng/mL. Proximal ligation of th...