Metallothioneins are small cysteine-rich proteins coordinating various transition metal ions preferably with the electron configuration d(10). They are ubiquitously present in all phyla, and next to phytochelatins they represent a successful molecular concept for high-capacity metal ion binding. Recent studies showed the incorporation of sulfide ions into the metal-thiolate cluster of metalloth...

Apart from the breast milk, infant formula and baby weaning food have a special role in infant diet. Infants and young children are very susceptible to amount of trace elements. Copper and zinc are two elements that add in infant food. Lead and cadmium are heavy metals that enter to food chain unavoidably. DPASV is a benefit and applicable method for measurement of trace elements in food produc...

Purified carboxypeptidase B contains 1 nondialyzable g atom of zinc per molecule based on a molecular weight of 34,300 (1). Inhibition studies with metal chelating agents have indicated that zinc is a functional component of this enzyme (1). The zinc may be replaced by cobalt or by cadmium and the resulting cobalt and cadmium enzymes have pronouncedly different actions toward specific peptide a...

The initial purification of metallothionein from equine renal cortex yielded preparations that were electrophoretically heterogeneous and contained 2.9% cadmium, 0.6% zinc, and 4.1% sulfur (1). By diethylaminoethyl cellulose column chromatography, we have now obtained electrophoretically and ultracentrifugally homogeneous metallothionein containing 5.9 ‘% cadmium, 2.2% zinc, and 8.5% sulfur. Mo...

BACKGROUND Toxic element exposure and essential trace element consumption may have changed after the Chinese economy transformed to a market-oriented system.The objectives of this study were to measure urinary concentrations of toxic (arsenic,cadmium, lead) and essential trace (selenium, zinc, copper) elements among rural residents in Hainan, China and to examine if variations in economic devel...

The X-ray structural chemistry of zinc and cadmium 1,1-dithiolates (for example, xanthate, dithiophosphate and dithiocarbamate) with potentially bridging bipyridyl-type ligands (for example, 4,4′-bipyridine) is reviewed. For zinc, the xanthates and dithiophosphates uniformly form one-dimensional coordination polymers, whereas the zinc dithiocarbamates are always zero-dimensional, reflecting the...

Metallothionein is an integral component of the mechanism that regulates the metabolism of cadmium and zinc. The synthesis of this protein can be "induced" by oral or parenteral administration of either metal. The metallothionein mRNA content of liver polysomes is increased shortly after an influx of small amounts of either metal into hepatocytes. After sufficient amounts of this poly (A+) RNA ...

In this study the effect of cadmium, cadmium+selenium and cadmium+zinc administration on the ovarian structure in Japanese quails was studied. The morphometric analysis of the relative volume of primary follicles detected the highest value in control group with a similar value in the group with administration of cadmium with selenium. Lower relative volume is reported in group with cadmium and ...

The individual and combined effects of copper, cadmium, and zinc on the cell division rate of the tropical freshwater alga Chlorella sp. were determined over 48 to 72 h. Metal mixtures were prepared based on multiples of their single-metal median effective concentration (EC50) values, i.e., toxic units (TU) using a triangular mixture design with five toxicant levels (0, 0.75, 1.0, 1.25, and 1.5...

The toxicity of cadmium and zinc at concentrations ranging from 0.1 to 100 microg/l was investigated against the activity of Diplostomum spathaceum (Rudolphi, 1819) cercariae. Over a 24 h exposure period a significant reduction in cercarial activity occurred in solutions of cadmium, zinc, and a mixture of cadmium and zinc at all concentrations. Reduced cercarial activity also occurred in all to...