oronary calcium assessment is being increasingly used in linical practice for risk stratification. Higher coronary alcium scores are associated with increased plaque burden nd increased cardiovascular risk. One concern is the presnce of isolated lipid-laden (soft) plaque in the setting of a egative study (zero calcium score). In this issue of the ournal, Hausleiter et al. (1) suggest that the a...

OBJECTIVES Our aim was to evaluate the atherosclerotic plaque burden and morphology as determined by 64-slice multislice computed tomography (MSCT) coronary angiography in relation to the calcium score in patients presenting with suspected acute coronary syndrome (ACS). BACKGROUND The absence of coronary calcium during coronary calcium scoring has been proposed to rule out significant coronar...

BACKGROUND Imaging of coronary plaques has traditionally focused on evaluating degree of stenosis, as the risk for adverse cardiac events increases with stenosis severity. However, the relation between plaque composition and severity of stenosis remains largely unknown. OBJECTIVE To assess plaque composition (non-invasively by multislice computed tomography (MSCT) angiography and invasively b...

Growth hormone (GH) secretion by the somatotrope is under dual regulation by the hypothalamic peptides, somatostatin (SS) and GH-releasing hormone (GHRH). Cytosolic free calcium concentration and cumulative GH release were measured simultaneously in anterior pituitary cells from adult male rats. This was made possible using a combination of digital imaging video microscopy with the fluorescent ...

The purpose of this study was to evaluate the relation between gender and plaque characteristics assessed by virtual histology-intravascular ultrasound (VH-IVUS) in patients with stable angina pectoris. Preinterventional VH-IVUS image was available for analysis in 88 men and 60 women patients. Women had significantly smaller vessel volume (12.7 ± 3.9 versus 14.5 ± 4.2 mm(3)/mm, P = .01) and sma...

OBJECTIVES The purpose of this study was to assess the relationship between carotid artery disease by ultrasound and coronary artery disease by coronary computed tomography angiography (CTA) and to identify carotid ultrasound parameters predictive of coronary artery disease. BACKGROUND Carotid ultrasound and CTA are noninvasive modalities used to image atherosclerosis. Studies examining the r...

BACKGROUND Calcification is a common finding in human coronary arteries; however, the relationship between calcification patterns, plaque morphology, and patterns of remodeling of culprit lesions in a comparison of patients with acute coronary syndromes (ACS) and those with stable conditions has not been documented. METHODS AND RESULTS Preinterventional intravascular ultrasound (IVUS) images ...

You have accessJournal of UrologyStone Disease: Basic Research & Pathophysiology (MP07)1 Sep 2021MP07-15 CALCIUM OXALATE STONE FORMERS WHO MAKE EVEN ONE ON RANDALL'S PLAQUE HAVE SMALLER BURDENS AND DISTINCTIVE PAPILLARY MINERAL PATHOLOGY James Williams, Haider Al-Awadi, Manognya Muthenini, Sharon Bledsoe, Tarek El-Achkar, Andrew Evan, Fredric Coe, Elaine Worcester, and Lingeman WilliamsJames Wi...

An 80-year-old man with a 1-day history of chest pain was referred to our cardiology clinic. The patient’s right arm blood pressure, pulse, and temperature were found to be 81/53 mm Hg, 71 beats/min, and 37.4°C, respectively. Electrocardiography was unremarkable. Chest radiography revealed a widened mediastinum and a small amount of pleural effusion at the left costophrenic angle (Figure A and ...

PURPOSE To correlate cardiovascular magnetic resonance (CMR)-based measurement of aortic pulse wave velocity (PWV) with serum markers for atherosclerosis and plaque burden in the thoracic aorta. METHOD Individuals with risk factors for coronary atherosclerosis underwent CMR pulse wave velocity examination of the descending thoracic aorta and computed tomography for coronary calcium scoring. I...