A phytochemical study on the flowe r of Calotropis gigantea (Linn.) using silica gel column chromatography and preparative thin layer chromatography, led to the first time isolation of Di-(2-ethylhexyl) phthalate (compound 1) and anhydrosophoradiol-3-acetate (compound 2). The structures of these compounds were confirmed by spectroscopic analyses (IR, HRTOFMS and NMR). The antibacterial and anti...

The protective effect of Calotropis gigantea flower extract in acute alcohol induced hepatotoxicity in rats was evaluated. A significant increase in the levels of enzyme markers of tissues damage (ALT, AST and ALP), lipid peroxidation (TBARS) and decreased serum vitamin C levels were observed in alcohol intoxicated rats as compared to control animals. Pretreatment with 250 and 500 mg/kg body we...

Keong mas atau Pomacea canaliculata (Lamarck) (Gastropoda: Ampullariidae) merupakan hama utama pada tanaman padi di Indonesia. Penggunaan serbuk daun pepaya (Carica papaya) dan biduri (Calotropis gigantea) dapat dijadikan sebagai moluskisida nabati alternatif untuk mengendalikan keong mas. Penelitian bertujuan mengetahui toksisitas tunggal dari serta campuran kedua tersebut dua macam perbanding...

Prolylcarboxypeptidase regulates proliferation, autophagy, and resistance to 4hydroxytamoxifen-induced cytotoxicity in ER-positive breast cancer cells Lei Duan, Natalia Motchoulski, Brian Danzer, Irina Davidovich, Zia Shariat-Madar, Victor V Levenson Department of Radiation Oncology, Rush University Medical Center, 1750 W Harrison Street, Chicago, IL60612. Department of Pharmacology, University...