نتایج جستجو برای: calyculin a
تعداد نتایج: 13431803 فیلتر نتایج به سال:
Blue light-induced oxygen uptake of the colorless mutant of Chlorella kessleri (No. 9.80) was 30-40% higher in the presence of exogenous glycine than in its absence. None of the other amino acids tested had this effect. Moreover, mutant cells in which glutamine synthetase was inhibited by methionine sulphoximine, accumulated approximately 65% more ammonium ions under blue irradiation in the pre...
Protein kinases in neutrophils that undergo changes in activity during cell stimulation have been investigated by two recently described procedures. These methods are based on the ability of renatured kinases to undergo autophosphorylation or to phosphorylate protein substrates fixed in gels. Using these techniques, we report that neutrophils contain a battery of protein kinases with molecular ...
Signal transducers and activators of transcription (STATs) are rapidly phosphorylated on tyrosine residues in response to cytokine and growth factor stimulation of cell surface receptors. STATs hereafter are translocated to the nucleus where they act as transcription factors. Recent reports suggest that serine phosphorylation of STATs also is involved in the regulation of STAT-mediated gene tra...
In cultured porcine aortic endothelial monolayers, the effect of ATP on myosin light chain (MLC) phosphorylation, which controls the endothelial contractile machinery, was studied. ATP (10 microM) reduced MLC phosphorylation but increased cytosolic Ca(2+) concentration ([Ca(2+)](i)). Inhibition of the ATP-evoked [Ca(2+)](i) rise by xestospongin C (10 microM), an inhibitor of the inositol trisph...
Phosphocalyculin C as a pyrophosphate protoxin of calyculin C in the marine sponge Discodermia calyx
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