Background and Objective: S100A8/A9 is a heterodimer calcium-binding protein which is involved in tumor cell proliferation, adhesion and invasion, and is proposed as a biomarker for better diagnosis and prognosis in many cancers. The aim of this study was to evaluate the simultaneous serum-based level of S100A8/A9 and CA15-3 as well-illustrated cancer biomarkers, as well as the...

  Background:The present study compared the differences between survivals of patients with colorectal cancer according to their ethnicity adjusted for other predictors of survival.   Methods: In this prospective cohort study patients were followed up from definite diagnosis of colorectal cancer to death. Totally, 2431 person-year follow-ups were undertaken for 1127 colorectal cancer patients on...

Introduction: The early diagnosis of breast cancer as prevalent cancer among women, is a necessity in the research on cancers since it could simplify the clinical management of other patients. The importance of the classification of breast cancer patients into high- or low-risk groups has led research groups in the biomedical and informatics departments to evaluate and use computer techniques s...

Introduction: The early diagnosis of breast cancer as prevalent cancer among women, is a necessity in the research on cancers since it could simplify the clinical management of other patients. The importance of the classification of breast cancer patients into high- or low-risk groups has led research groups in the biomedical and informatics departments to evaluate and use computer techniques s...

Based on a life course framework we propose that a cancer diagnosis is associated with increased religiosity and that this relationship is contingent upon three social clocks: cohort (1920-1945, 1946-1964, 1964+), age-at-diagnosis, and years-since-diagnosis. Using prospective data from the National Survey of Midlife Development (N=3443), taken in 1994-1995 and 2004-2006, we test these arguments...

A considerable number of patients with cancer have used or are using the Gerson therapy, an alleged anticancer metabolic diet. However, there is almost no scientific support for this regimen. Hence, the present case review study of 6 patients with metastatic cancer who used the Gerson therapy aims at critically evaluating each case to derive some valid interpretations of its potential effect. A...

This paper sets out to review the influence of social processes on the timing of the diagnosis of cancer and to explore the potential for promoting earlier diagnosis by addressing social factors that influence symptom recognition and the diagnostic process. Social processes refer to the means by which culture and social organisation may impact on timely cancer diagnosis. The paper calls for con...

compared to western countries, pancreatic cancer has a relatively low incidence in iran. it is rarely diagnosed before the fifth decade in iran and most of the patients are older than 60 at the time of diagnosis like to the western countries, where pancreatic cancer is a disease of advanced age. the incidence of the disease in some young patients suggests a possible role of genetic defects, whi...

background: idiopathic granulomatous mastitis (igm) is a rare benign breast disease, which can mimic breast cancer. as the managements of igm and breast cancer are entirely different and the initial clinical manifestations are similar in several cases, it is very important to differentiate them. case presentation: we reported a 48-year-old female patient with igm and breast cancer. she was refe...