There has been a sharp rise in the occurrence of Candida infections and associated mortality over the last few years, due to the growing body of immunocompromised population. Limited number of currently available antifungal agents, undesirable side effects and toxicity, as well as emergence of resistant strains pose a considerable clinical challenge for the treatment of candidiasis. Therefore, ...

Candida species uncommonly cause vertebral osteomyelitis. We present a case of lumbar vertebral osteomyelitis caused by Candida albicans and review 59 cases of candidal vertebral osteomyelitis reported in the literature. The mean age was 50 years, and the lower thoracic or lumbar spine was involved in 95% of patients. Eighty-three percent of patients had back pain for >1 month, 32% presented wi...

Increasing use of short-course antifungal therapies in patients with recurrent vulvovaginitis may enable the emergence of less-common, more resistant yeast strains as vaginal pathogens. We report the case of a patient with chronically symptomatic and repeatedly treated vaginal candidiasis whose infection was attributable to Candida lusitaniae, a previously unreported cause of candidal vaginitis.

In a trial of natamycin, an antifungal antibiotic in a vanishing cream base, assessment was possible in 66 men with genital or anal candidosis. The overall cure rate was 82 percent, In 43 patients with culturally proven candidosis it was 98 percent. but in 23 patients treated solely on clinical impression it was only 52 percent. Symptoms were rapidly relieved in those who responded and there we...

Colonization of soft lining materials with microorganisms, espe­ cially Candida albicans, is a common clinical problem. Silicone­based soft li ning materials have been found to be particularly susceptible to Candi­ dal adhesion. This study investigated the Candida albicans adhesion to 6 silicone­based soft lining materials (Molloplast­B, Mollosil, Ufigel P, Ufigel C, Soft Liner and Luci­sof). F...

Methods. Skin scrapings were taken from outpatients with superficial dermatomycoses and cultured in Sabouraud dextrose agar with cycloheximide. They were then evaluated under a microscope using both the KOH wet mount technique and the new contrast stain. Two investigators read the slides together but were blinded to all other test results. The new contrast stain contains 1% Chicago sky blue 6B ...

INTRODUCTION Facial candidal abscess is an infection with a fungal cause which was presented in this case such a rarity. We report a rare case of facial abscess due to Candida species in a patient with unknown diabetes. MATERIALS AND METHODS The patient presented with a longstanding firm swelling which occurred 2 weeks ago and did not show any improvement of healing process in spite of surgic...

Five hundred clinical specimens of sputa, bronchial aspirations, and pleural effusions were collected from hospitalized tuberculous patients for the isolation of Candida species. The patients were categorized in two groups. Group A included tuberculous patients having some complications like nonsubsiding fever, marked cough and persistence of other symptoms in spite of taking antituberculous tr...

Invasive candidal infections are encountered with increasing frequency in compromised hosts but bone infection is uncommon. A woman with systemic lupus erythematosus and end-stage renal failure managed by continuous ambulatory peritoneal dialysis developed a painful thoracic kyphosis and a lytic lesion in the vertebral bodies of T10 and T11. Blood cultures were sterile but bone biopsy material ...

Five cases of candidal meningitis in human immunodeficiency virus (HIV)-infected patients have been diagnosed in our hospital. This article describes these cases and reviews another nine previously reported in the literature. Most patients (71%) had at least one well-known predisposing factor for candidiasis. Median CD4 cell count was 135/mm3. Headache and fever, in the absence of focal neurolo...